Entry - 603979 - ZINC FINGER PROTEIN 97; ZNF97 - OMIM

 
 
603979

ZINC FINGER PROTEIN 97; ZNF97


Cytogenetic location: Chr.19     Genomic coordinates (GRCh38): 19:1-58,617,616


TEXT

▼ Description

The ZNF97 gene encodes a zinc finger protein of the KRAB (Kruppel-associated box) subfamily (Bellefroid et al., 1993). See ZNF91 (603971) for general information on ZNFs.


▼ Cloning and Expression

Using probes derived from a ZNF91 cDNA to screen a pool of human chromosome 19-specific cosmids that had hybridized to a degenerate oligonucleotide corresponding to the H/C link region, Bellefroid et al. (1993) isolated the genes of several distinct ZNF91 subfamily members, including ZNF97. They found that ZNF91-related genes are widely expressed in human tissues, with the highest expression in T-lymphoid cells.


▼ Mapping

Bellefroid et al. (1993) mapped YAC clones containing ZNF91-related genes by FISH and found that most of these genes, including ZNF97, are clustered in 19p13.1-p12.


▼ REFERENCES

  1. Bellefroid, E. J., Marine, J. C., Ried, T., Lecocq, P. J., Riviere, M., Amemiya, C., Poncelet, D. A., Coulie, P. G., de Jong, P., Szpirer, C., Ward, D. C., Martial, J. A. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. EMBO J. 12: 1363-1374, 1993. [PubMed: 8467795, related citations] [Full Text]


Creation Date:
Patti M. Sherman : 7/9/1999
Edit History:
carol : 02/25/2020
carol : 03/28/2014
mgross : 7/20/1999
mgross : 7/13/1999
psherman : 7/9/1999

603979

ZINC FINGER PROTEIN 97; ZNF97


Cytogenetic location: Chr.19     Genomic coordinates (GRCh38): 19:1-58,617,616


TEXT

Description

The ZNF97 gene encodes a zinc finger protein of the KRAB (Kruppel-associated box) subfamily (Bellefroid et al., 1993). See ZNF91 (603971) for general information on ZNFs.


Cloning and Expression

Using probes derived from a ZNF91 cDNA to screen a pool of human chromosome 19-specific cosmids that had hybridized to a degenerate oligonucleotide corresponding to the H/C link region, Bellefroid et al. (1993) isolated the genes of several distinct ZNF91 subfamily members, including ZNF97. They found that ZNF91-related genes are widely expressed in human tissues, with the highest expression in T-lymphoid cells.


Mapping

Bellefroid et al. (1993) mapped YAC clones containing ZNF91-related genes by FISH and found that most of these genes, including ZNF97, are clustered in 19p13.1-p12.


REFERENCES

  1. Bellefroid, E. J., Marine, J. C., Ried, T., Lecocq, P. J., Riviere, M., Amemiya, C., Poncelet, D. A., Coulie, P. G., de Jong, P., Szpirer, C., Ward, D. C., Martial, J. A. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. EMBO J. 12: 1363-1374, 1993. [PubMed: 8467795] [Full Text: https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0261-4189&date=1993&volume=12&issue=4&spage=1363]


Creation Date:
Patti M. Sherman : 7/9/1999

Edit History:
carol : 02/25/2020
carol : 03/28/2014
mgross : 7/20/1999
mgross : 7/13/1999
psherman : 7/9/1999



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: June 4, 2024