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Transporter, Adenosine Eurofins Panlabs panel
Assay data:1 Tested
Summary
Serotonin (5-Hydroxytryptamine) 5-HT4 Eurofins Panlabs panel
SummaryRelated BioAssays by Target
Leukotriene LTC4 Synthase Eurofins Panlabs panel
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane assessed as inhibition constant
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane assessed as inhibition constant measured for 150 mins
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane assessed as inhibition constant measured after 120 mins by scintillation counting method
Assay data:5 Active, 2 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane assessed as inhibition constant measured for 150 mins in presence of haloperidol
Assay data:10 Active, 1 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Inhibition of superoxide anion radical release in guinea pig peritoneal macrophages
Assay data:11 Tested
Antihistamine activity against conscious unrestrained ovalbumin and aluminum hydroxide sensitized guinea pigs assessed as inhibition of histamine-induced nasal congestion at 1 mg/ml, intranasal measured after 1 to 24 hrs relative to control
Assay data:2 Active, 2 Tested
Antihistamine activity against conscious unrestrained ovalbumin and aluminum hydroxide sensitized guinea pigs assessed as inhibition of histamine-induced nasal congestion by measuring time duration of action at 1 mg/ml, intranasal measured after 1 to 24 hrs
Assay data:2 Tested
Antagonist activity at histamine H1 receptor in guinea pig isolated trachea assessed as change in histamine-induced contraction
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Toxicity in langendorff-perfused guinea pig heart assessed as effect on left atrial action potential duration at 10 uM
Toxicity in langendorff-perfused guinea pig heart assessed as effect on left ventricular action potential duration at 10 uM
Toxicity in langendorff-perfused guinea pig heart assessed as effect on QT interval at 10 uM
Toxicity in langendorff-perfused guinea pig heart assessed as effect on coronary artery perfusion pressure at 10 uM
Toxicity in langendorff-perfused guinea pig heart assessed as effect on PR interval at 10 uM
Effect on fingolimod-induced shortening of AERP in guinea pig model assessed as prolongation of shortened AERP at 3 mg/kg, iv measured at 20 to 30 mins
Assay data:1 Active, 1 Tested
Effect on AERP in guinea pig assessed as increase in AERP interval at 3 mg/kg, iv measured for 60 mins
Effect on fingolimod-induced shortening of AERP in guinea pig model assessed as restoration of shortened AERP measured at 30 to 60 mins
Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane assessed as inhibition constant incubated for 120 mins
Assay data:11 Active, 11 Activity ≤ 1 µM, 12 Tested
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