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BVDV antiviral and plaque assays from US Patent US10376502: "Alkylated imino sugars exhibiting glucosidase inhibition and their method of use"
Assay data:17 Active, 13 Activity ≤ 1 µM, 20 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Antiviral activity against Bovine viral diarrhea virus NADL ATCC VR 534 infected in bovine MDBK cells assessed as protection against virus-induced cytopathic effect after 3 to 4 days by MTT assay
Assay data:5 Active, 31 Tested
SummaryCompounds, ActivePubMed Citation
Antiviral activity against BVDV NADL ATCC VR-534 infected in MDBK cells assessed as protection against virus-induced cytopathic effect after 3 to 4 days by MTT assay
Assay data:2 Active, 10 Tested
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDBK cells assessed as inhibition of post viral entry pre-budding stage of replication administered at 13 hrs post infection measured after 24 to 36 hrs by plaque reduction assay
Assay data:1 Active, 1 Tested
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDBK cells assessed as inhibition of viral replication administered up to 4 hrs post infection measured after 24 to 36 hrs by plaque reduction assay
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDBK cells assessed as protection from virus-induced cytopathogenicity administered up to 6 hrs post infection measured after 24 to 36 hrs by plaque reduction assay
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDBK cells assessed as protection from virus-induced cytopathogenicity after 3 to 4 days by MTT method
Assay data:22 Active, 4 Activity ≤ 1 µM, 79 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDCK cells at 2 uM by plaque reduction assay relative to control
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDCK cells at 4 uM by plaque reduction assay relative to control
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDCK cells at 8 uM by plaque reduction assay relative to control
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDCK cells at 0.001 multiplicity of infection assessed as protection against virus-induced cytopathogenic effect at 5 uM relative to control
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDCK cells at 0.01 multiplicity of infection assessed as protection against virus-induced cytopathogenic effect at 5 uM relative to control
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDCK cells at 0.1 multiplicity of infection assessed as protection against virus-induced cytopathogenic effect at 5 uM relative to control
Assay data:1 Tested
SummaryPubMed Citation
Antiviral activity against Bovine viral diarrhea virus NADL infected in MDCK cells at 1 multiplicity of infection assessed as protection against virus-induced cytopathogenic effect at 5 uM relative to control
Antiviral activity against Bovine viral diarrhea virus 1-NADL infected in bovine MDBK cells assessed as reduction in plaque forming units after 72 hrs by crystal violet staining-based assay
Assay data:11 Active, 1 Activity ≤ 1 µM, 18 Tested
Antiviral activity against BVDV NADL infected in MDBK cells assessed as inhibition of virus induced cytopathogenicity after 3 to 4 days by MTT assay
Assay data:24 Active, 2 Activity ≤ 1 µM, 35 Tested
Antiviral activity against Bovine viral diarrhea virus 1-NADL ATCC VR-534 infected in MDBK cells assessed as protection against virus-induced cytopathogenicity after 3 to 4 days by MTT assay
Assay data:1 Active, 32 Tested
Antiviral activity against Bovine viral diarrhea virus 1-NADL ATCC VR-534 infected in MDBK cells assessed as protection from virus-induced cytopathogenicity after 3 to 4 days by MTT method
Assay data:6 Active, 19 Tested
Antiviral activity against 1 MOI BVDV NADL infected in MDBK cells assessed as reduction in viral titer after 22 hrs
Assay data:46 Active, 25 Activity ≤ 1 µM, 50 Tested
Antiviral activity against Bovine viral diarrhea virus 1-NADL ATCC VR534 infected in MDBK cells assessed as reduction of viral cytopathic effect after 2 days bt MTS assay
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