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Inhibition Assays from Article 10.1016/j.chembiol.2015.08.005: "Structure and Inhibition of Microbiome -Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity."
Assay data:10 Active, 7 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antibacterial activity against Clostridium perfringens CECT376 incubated for 24 hrs by CLSI based broth microdilution method
Assay data:3 Active, 2 Activity ≤ 1 µM, 38 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antibacterial activity against Clostridium perfringens 22 incubated for 18 hrs by microbroth dilution method
Assay data:1 Tested
SummaryPubMed Citation
Antibacterial activity against Clostridium perfringens CICC 22949 assessed as inhibition of bacterial growth incubated for 24 hrs by broth microdilution method
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Increase in Melting temperature (delta Tm) for Clostridium perfringens DNA on interaction against ligand (mole ratio of 10:1)
Assay data:7 Tested
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509
Summary
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (value is 68RC - RC: Resistant colonies present)
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (value is 35RC - RC: Resistant colonies present)
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (value is 29RC - RC: Resistant colonies present)
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (value is 23RC - RC: Resistant colonies present)
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (value is 100RC - RC: Resistant colonies present)
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (value: 105RC - RC: Resistant colonies present)
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (Vaue is 45RC - RC: Resistant colonies present)
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (RC - Resistant colonies present)
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (33H -, H: Hazy zone)
Assay data:2 Tested
The compound (1 mg/mL, 80 microL/12.7 mm) was tested for zone of inhibition against Clostridium perfringens UC6509 (22H -, H: Hazy zone)
Tested for zone of inhibition against Clostridium perfringens UC6509
Assay data:18 Tested
Antibacterial activity against Clostridium perfringens ATCC 13124 incubated for 48 hrs under anaerobic condition by MTT assay
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Inhibition of clostridium perfringens OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by addition of substrate and measured after 6 hrs by fluorescence assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of clostridium perfringens neuraminidase using fluorescent substrate preincubated for 2 mins followed by substrate addition and measured after 1 hr by fluorescence based microplate reader analysis
Assay data:4 Active, 1 Activity ≤ 1 µM, 15 Tested
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