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Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB
Assay data:4302 Active, 250 Activity ≤ 1 nM, 2931 Activity ≤ 1 µM, 4302 Tested
Nrf2 qHTS screen for inhibitors: Purified Fluc Biochemical Counterscreen for Hit Validation
Assay data:58 Active, 10 Activity ≤ 1 µM, 1359 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Summary of HTS Screening Project for Inhibitors of fluorogen-FAP tag interactions
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Fluorogen/soluble FAP binding competition assay
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Evaluation of reversibility of compound binding to AM2.2-beta2AR cells with Powder Set 3and4
Assay data:12 Active, 12 Tested
Late stage probe development counterscreen for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3): real-time florescence-based biochemical assay to determine whether compounds inhibit the helicase encoded by one or more HCV strains: Set 3
Assay data:68 Active, 3 Activity ≤ 1 µM, 82 Tested
Late stage counterscreen results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): Radioactivity-based biochemical assay to identify modulators of a panel of 48 kinases
Assay data:1 Tested
Late stage probe development counterscreen for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3): real-time florescence-based biochemical assay to determine whether compounds inhibit the helicase encoded by one or more HCV strains: Set 2
Assay data:16 Active, 3 Activity ≤ 1 µM, 69 Tested
uHTS fluorescence for the identification of compounds that decrease EGFP protein stability
Assay data:39 Active, 429 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
Late stage probe development counterscreen for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3): real-time florescence-based biochemical assay to determine whether compounds inhibit the helicase encoded by one or more HCV strains
Assay data:16 Tested
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
SummaryCompounds, ActivePubMed Citation
Summary of the probe development efforts to identify chemical inhibitors of antigen receptor-induced NF-?B activation
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