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In Vitro Radioligand Binding Assay from US Patent US20240208984: "BIVALENT LIGANDS TO UNDERSTAND DIMERIZATION OF THE MU OPIOID RECEPTOR AND THE CHEMOKINE RECEPTOR CCR5 IN NEUROLOGICAL DISORDERS"
Assay data:6 Active, 1 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
Summary
beta-lactamase assay from US Patent US10543221: "Beta-lactamase inhibitors, formulations, and uses thereof"
Assay data:6 Active, 1 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Isothermal Titration Calorimetry (ITC) from Article 10.1074/jbc.M113.487777: "Roles of phosphate recognition in inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) substrate binding and activation."
Assay data:3 Active, 1 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Arabidopsis thaliana expressed-sequence-tagged PDF2 using for-Met-Ala-Ser as substrate preincubated for 10 mins followed by substrate addition in presence of NAD+ and measured after 10 mins by absorbance analysis
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of Arabidopsis thaliana STRS2 helicase activity
Assay data:2 Tested
SummaryPubMed Citation
PP2C Activity Assay from US Patent US10167261: "2-oxo-3,4-dihydroquinolin-6-yl sulphonamide CPDS and their use as plant growth regulators"
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Inhibition of Arabidopsis thaliana HPPD
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Growth inhibition of Arabidopsis thaliana var. Columbia after 9 days by agarose-based test
Assay data:8 Tested
Phytotoxicity against Arabidopsis thaliana Col-4 leaves assessed as induction of leaf death after 7 weeks post compound application by detached leaf assay
Assay data:9 Active, 2 Activity ≤ 1 µM, 22 Tested
Phytotoxicity against Arabidopsis thaliana Col-4 leaves assessed as induction of chlorosis, shriveling or death of leaves after 7 weeks post compound application by detached leaf assay
Assay data:9 Active, 16 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of Arabidopsis thaliana root growth
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Metabolite reversal in Arabidopsis thaliana assessed as root growth inhibition in presence of adenine
Assay data:1 Active, 1 Tested
Metabolite reversal in Arabidopsis thaliana assessed as root growth inhibition in presence of adenine and guanine
Assay data:1 Tested
Mitochondrial uncoupling activity in Arabidopsis root cells assessed as inhibition of clathrin-mediated endocytosis by measuring reduction of FM4-64 uptake
Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using HPPA as substrate after preincubated for 15 min followed by substrate addition by HPLC analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM109 using HPPA as substrate after 10 mins
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli BL21(DE3) using HPPA as substrate after 10 mins by UV-Vis spectrometric analysis
Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested
Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using 4-HPP as substrate preincubated for 15 mins followed by substrate addition measured after 15 mins by HPLC analysis
Assay data:3 Active, 3 Activity ≤ 1 µM, 4 Tested
Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli T7 expression system using HPPA as substrate preincubated for 30 mins followed by substrate addition measured for 20 mins by HGA dioxygenase enzyme coupled spectrophotometric method
Inhibition of Arabidopsis thaliana SHMT using L-serine/(6S)-THF as substrate after 20 mins by methylene tetrahydrofolate dehydrogenase coupled enzyme assay
Assay data:20 Active, 1 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 23 Tested
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