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Antiparasitic activity against Entamoeba histolytica trophozoites infected in hamster liver to induce hepatic abscess assessed as reduction in liver abscess formation at 10 mg/kg, ip for 5 days
Assay data:1 Tested
SummaryPubMed Citation
Antiparasitic activity against Entamoeba histolytica trophozoites assessed as parasite growth inhibition incubated for 90 hrs followed by [3H]hypoxanthine addition and measured after 6 hrs by scintillation counter analysis
Assay data:2 Active, 8 Tested
SummaryCompounds, ActivePubMed Citation
Lowest active dose which cured rats with Entamoeba histolytica cecal infection was measured
Assay data:9 Tested
Lowest active dose which cured hamsters with Entamoeba histolytica hepatic infection was measured
Assay data:6 Tested
Antiamoebic activity against Entamoeba histolytica HM-1:IMSS trophozoites incubated for 2 days under anaerobic condition
Assay data:2 Active, 2 Tested
Antiamoebic activity against Entamoeba histolytica HM-1:IMSS trophozoites measured after 72 hrs by microdilution method
Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiamoebic activity against Entamoeba histolytica HK9 ATCC 30015 by trypan blue staining based assay
Assay data:8 Active, 1 Activity ≤ 1 µM, 8 Tested
Antiamoebic activity against Entamoeba histolytica HK9 ATCC 30015 incubated for 72 hrs by trypan blue staining based assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 5 Tested
Antimicrobial activity against Entamoeba histolytica HM1:MMS assessed as reduction in amoeba growth incubated for 72 hrs by microscopy analysis
Assay data:14 Active, 3 Activity ≤ 1 µM, 14 Tested
Antimicrobial activity against Entamoeba histolytica HM1:MMS assessed as reduction in amoeba growth
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
Antiparasitic activity against Entamoeba histolytica HM-1:IMSS trophozoites after 24 to 48 hrs by CellTiter-Glo luminescent cell viability assay
Assay data:18 Active, 50 Tested
Antiparasitic activity against Entamoeba histolytica HM1-IMSS trophozoites assessed as inhibition of parasitic growth treated for 48 hrs followed by compound washout and measured after 48 hrs by MTT/PMS dye based colorimetric method
Assay data:2 Active, 1 Activity ≤ 1 µM, 8 Tested
Antiparasitic activity against Entamoeba histolytica clinical isolate after 24 hrs under anaerobic cinditions
Anti-amoebic activity against trophozoites of Entamoeba histolytica HM-1:IMSS gassed with nitrogen for 10 mins measured after 72 hrs by eosin staining based micro dilution method
Assay data:13 Active, 7 Activity ≤ 1 µM, 15 Tested
Antiparasitic activity against Entamoeba histolytica HM-1:IMSS trophozoites assessed as parasite growth inhibition after 48 hrs by ATP bioluminescence-based CellTiter-Glo luminescent cell viability assay
Assay data:1 Active, 2 Tested
Antiamoebic activity against trophozoite stage of Entamoeba histolytica HM-1:IMSS measured after 72 hrs by microdilution method
Assay data:23 Active, 6 Activity ≤ 1 µM, 23 Tested
Antiparasitic activity against trophozoite stage of Entamoeba histolytica HM-1:IMSS after 48 hrs by haemocytometric method
Assay data:7 Active, 5 Activity ≤ 1 µM, 8 Tested
Antiparasitic activity against trophozoite stage of Entamoeba histolytica HM-1:IMSS after 48 hrs
Assay data:13 Active, 13 Activity ≤ 1 µM, 14 Tested
Antiamoebic activity against Entamoeba histolytica HM-1:IMSS trophozoites incubated for 10 mins under nitrogen gassed condition measured after 72 hrs by eosin staining based micro dilution method
Assay data:30 Active, 3 Activity ≤ 1 µM, 30 Tested
Inhibition of Entamoeba histolytica O-acetyl-L-serine sulfohydrolase preincubated with enzyme followed by TNB substrate addition measured after 30 mins by UV-Visible spectrophotometric method
Assay data:12 Tested
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