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Inhibition of Haemophilus influenzae DapE at 75 uM relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Haemophilus influenzae DapE at 100 uM relative to control
Assay data:13 Tested
Inhibition of Haemophilus influenzae DapE
Assay data:5 Tested
Inhibition of Haemophilus influenzae ATCC 51907 FabI assessed as by measuring NADH consumption rate
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
ScintillationProximity_Assay from Article : "GSK TrmD"
Assay data:23 Active, 12 Activity ≤ 1 µM, 31 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Inhibition Assay from Article 10.1074/jbc.M111.274068: "In vitro validation of acetyltransferase activity of GlmU as an antibacterial target in Haemophilus influenzae."
Assay data:5 Active, 3 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
FabD/FabH Coupled Assay from Article 10.1021/jm049141s: "Structure-based design, synthesis, and study of potent inhibitors of beta-ketoacyl-acyl carrier protein synthase III as potential antimicrobial agents."
Assay data:35 Active, 19 Activity ≤ 1 µM, 46 Tested
PDF Inhibition Assay from Article 10.1110/ps.0229303: "Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species."
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Homogeneous Enzyme Assay with SPA Beads from Article 10.1016/j.bmcl.2005.03.003: "Discovery and optimisation of potent, selective, ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase."
Assay data:43 Active, 43 Activity ≤ 1 µM, 45 Tested
Enzyme Inhibition Assay from Article 10.1021/jm0204035: "Indole naphthyridinones as inhibitors of bacterial enoyl-ACP reductases FabI and FabK."
Assay data:11 Active, 9 Activity ≤ 1 µM, 11 Tested
Enzyme Inhibition Assay from Article 10.1021/jm020050+: "Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI)."
Assay data:9 Active, 1 Activity ≤ 1 µM, 15 Tested
Inhibition of Haemophilus influenza HmrM transporter expressed in Escherichia coli KAM32 assessed as inhibition of bacterial resistance to norfloxacin by measuring reduction in bacterial growth at 100 uM incubated for 18 hrs by microbroth dilution method (Rvb = 0%)
Assay data:20 Tested
SummaryPubMed Citation
Inhibition of Haemophilus influenza HmrM transporter expressed in Escherichia coli KAM32 assessed as inhibition of bacterial resistance to norfloxacin by measuring norfloxacin MIC at 100 uM incubated for 18 hrs by microbroth dilution method (Rvb = 64 ng/ml)
Inhibition of Haemophilus influenzae Rd IGA1 protease expressed in Escherichia coli BL21(DE3) preincubated for 1 hr followed by substrate addition and measured after 2 hrs by sandwich ELISA
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Haemophilus influenzae MetRS
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of Haemophilus influenzae recombinant DapE by competitive binding assay
Assay data:2 Active, 3 Tested
Inhibition of Haemophilus influenzae recombinant DapE
Assay data:1 Active, 16 Tested
Binding affinity to Haemophilus influenzae O-acetylserine sulfhydrylase expressed in Escherichia coli BL21 (DE3) by fluorescence emission spectra analysis
Assay data:14 Tested
Inhibition of Haemophilus influenzae Hind 3 assessed as undigested supercoiled pBR322 DNA concentration
Assay data:4 Tested
Inhibitory concentration against Haemophilus influenzae Phenylalanyl-tRNA synthetase
Assay data:3 Active, 3 Activity ≤ 1 µM, 4 Tested
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