Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Cytotoxicity against human MT4 cells assessed as reduction in cell viability by celltiter-glo luminescent cell viability assay
Assay data:1 Active, 13 Tested
SummaryCompounds, ActivePubMed Citation
Antiproliferative activity against human MM1.R cells assessed as inhibition of cell proliferation incubated for 72 hrs by XTT assay
Assay data:5 Active, 2 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiproliferative activity against human MM1.S cells assessed as inhibition of cell proliferation incubated for 72 hrs by XTT assay
Assay data:4 Active, 2 Activity ≤ 1 µM, 5 Tested
Antiproliferative activity against human RPMI-8226 cells assessed as inhibition of cell proliferation incubated for 72 hrs by XTT assay
Assay data:4 Active, 2 Activity ≤ 1 µM, 8 Tested
Agonist activity at FXR (unknown origin) assessed as transactivation by measuring increase in fluorescein-labelled coactivator SRC-2 peptide recruitment by Lanthascreen TR-FRET assay
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at RXRbeta-LBD (unknown origin) assessed as transactivation by measuring increase in fluorescein-labelled coactivator D22 peptide recruitment by Lanthascreen TR-FRET assay
Agonist activity at RXRalpha-LBD (unknown origin) assessed as transactivation by measuring increase in fluorescein-labelled coactivator PGC-1alpha peptide recruitment by Lanthascreen TR-FRET
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at RXRalpha-LBD (unknown origin) assessed as transactivation by measuring increase in fluorescein-labelled coactivator PGC-1alpha peptide recruitment at 60 uM by Lanthascreen TR-FRET assay relative to control
Assay data:1 Tested
Partial agonist activity at PPARdelta (unknown origin) assessed as increase in fluorescein labeled PRIP/RAP250 coactivator peptide requirement by Lanthascreen TR-FRET assay
Partial agonist activity at PPARdelta (unknown origin) assessed as increase in fluorescein labeled SMRT corepressor peptide requirement by Lanthascreen TR-FRET assay
Partial agonist activity at PPARalpha (unknown origin) assessed as increase in fluorescein labeled SMRT corepressor peptide requirement by Lanthascreen TR-FRET assay
Partial agonist activity at PPARgamma (unknown origin) assessed as increase in fluorescein labeled SMRT corepressor peptide requirement by Lanthascreen TR-FRET assay
Partial agonist activity at PPARgamma (unknown origin) assessed as increase in fluorescein labeled SRC-2 coactivator peptide requirement by Lanthascreen TR-FRET assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Partial agonist activity at PPARgamma (unknown origin) assessed as increase in fluorescein labeled SRC-1 coactivator peptide requirement by Lanthascreen TR-FRET assay
Partial agonist activity at PPARgamma (unknown origin) assessed as increase in fluorescein labeled PRIP/RAP250 coactivator peptide requirement by Lanthascreen TR-FRET assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 4 Tested
Partial agonist activity at PPARalpha (unknown origin) assessed as increase in PRIP/RAP250 coactivator peptide requirement by Lanthascreen TR-FRET assay
Partial agonist activity at PPARgamma in human BMMSC cells assessed as inhibition of pioglitazone-induced adiponectin synthesis measured after 5 days by ELISA
Binding affinity to PPARdelta (unknown origin) assessed as inhibition constant by Cheng-Prusoff equation analysis
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 4 Tested
Binding affinity to PPARgamma (unknown origin) assessed as inhibition constant by Cheng-Prusoff equation analysis
Assay data:3 Active, 2 Activity ≤ 1 µM, 4 Tested
Binding affinity to PPARalpha (unknown origin) assessed as inhibition constant by Cheng-Prusoff equation analysis
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on