Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Cytotoxicity against IL2 independent FL-4 cells assessed as reduction in cell viability measured after 7 days by MTT assay
Assay data:3 Active, 33 Tested
SummaryCompounds, ActivePubMed Citation
Cytotoxicity against FEA cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Assay data:4 Active, 33 Tested
Cytotoxicity against CRFK cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Assay data:2 Active, 33 Tested
Drug uptake in cat striatum at 2.5 mCi, iv measured upto 90 mins by PET imaging
Assay data:1 Tested
SummaryPubMed Citation
Drug uptake ratio in cat brain dorsal raphe nucleus to cerebellum measured after 20 to 30 mins by camera ClearPET LYSO/LuYAP Phoswich-scanner analysis
Effect on 2 Hz transmural stimulation of right atrium-induced positive chronotropic response in cat assessed as inhibition of change in heart rate
Assay data:3 Tested
Neuromuscular blocking activity in cat assessed as blockade of tibialis muscle twitches
Assay data:8 Tested
Agonist activity at dopamine receptor in cat right atrium assessed as inhibition of cardiaccelerator nerve stimulation rate by cardiotachometer analysis
Assay data:4 Tested
Cytotoxicity against cat CRFK cells assessed as reduction in cell viability after 5 days by MTT assay
Cmax in cat administered at 0.5 mg/kg, sc
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibitory potency in anesthetized cats
Assay data:9 Tested
Inhibition of superior cervical nerve-induced contractions of the nictitating membrane
Assay data:5 Tested
Inhibition of stimulated vagus nerve-induced bradycardia
In vitro effect on Gamma-aminobutyric acid agonism on single neurons of cat spinal cord (0 is no significant activity)
Assay data:2 Tested
Inhibition of stimulation-induced tachycardia via the presynaptic dopamine receptors
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Neuromuscular blocking property by complete spontaneous reversal in anesthetized cats;
Assay data:12 Tested
Ability to lower arterial blood pressure in cat at 200 ug/kg; reversed
Ability to lower arterial blood pressure in cat at 100 ug/kg; reversed
Compound was evaluated for its action blockade by haloperidol (0.1 mg/kg); yes
Neuromuscular blocking property by neostigmine reversal in anesthetized cats at dose of 0.55 mg/Kg;
Assay data:11 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on