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Inhibition of Peptidase, Angiotensin Converting Enzyme at 10.0 M in the Eurofins Panlabs Safety Screen
Assay data:1 Tested
SummaryRelated BioAssays by Target
Activity against Y2/RB in the Eurofins Panlabs screen (BI) by Radioactive Assay
Summary
Activity against TXA2/RB in the Eurofins Panlabs screen (BI) by Radioactive Assay
Activity against PAF/RB in the Eurofins Panlabs screen (BI) by Radioactive Assay
Activity against M4/RB in the Eurofins Panlabs screen (BI) by Radioactive Assay
Activity against BETA1/RB in the Eurofins Panlabs screen (BI) by Radioactive Assay
Activity against ATII/RB in the Eurofins Panlabs screen (BI) by Radioactive Assay
Activity against ALPHA2A/RB in the Eurofins Panlabs screen (BI) by Radioactive Assay
Activity against 5HT3/RB in the Eurofins Panlabs screen (BI) by Radioactive Assay
Inhibitor of 15LO in the Eurofins Panlabs screen (BI) by absorption of electromagnetic radiation
Activity against P2X/R in the Eurofins SafetyScreen44 (BI) by Others (Old_Cerep_29)
Antithrombotic activity FeCl3-induced thrombosis New Zealand white rabbit model assessed as reduction on thrombus weight by measuring effective dose at iv administration and measured after 60 mins
SummaryPubMed Citation
Antithrombotic activity FeCl3-induced thrombosis New Zealand white rabbit model assessed as reduction on thrombus weight at 30 mg/kg,po administration and measured after 60 mins
Antithrombotic activity FeCl3-induced thrombosis New Zealand white rabbit model assessed as reduction on thrombus weight at 10 mg/kg,po administration and measured after 60 mins
Antithrombotic activity FeCl3-induced ear injury bleeding New Zealand white rabbit model assessed as effect on ear bleeding at 0.6 to 20 mg/kg,iv administrated in presence of ticagrelor and measured after 60 mins
Antithrombotic activity FeCl3-induced ear injury bleeding New Zealand white rabbit model assessed as effect on ear bleeding at 0.6 to 20 mg/kg,iv administrated in presence of aspirin and measured after 60 mins
Antithrombotic activity FeCl3-induced thrombosis New Zealand white rabbit model assessed as reduction on thrombus weight at 0.6 to 20 mg/kg,iv administrated in presence of ticagrelor and measured after 60 mins
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Antithrombotic activity FeCl3-induced thrombosis New Zealand white rabbit model assessed as reduction on thrombus weight at 0.6 to 20 mg/kg,iv administrated in presence of aspirin and measured after 60 mins
Antithrombotic activity FeCl3-induced ear injury bleeding New Zealand white rabbit model assessed as effect on ear bleeding at 0.6 to 20 mg/kg,iv administration and measured after 60 mins
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