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NanoBRET (AKT3)
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
AKT3 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of AKT3 (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of AKT expression in human MDA-MB-231 cells at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of AKT phosphorylation in human MDA-MB-231 cells at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis
Inhibition of AKT phosphorylation in human Jurkat cells incubated for 1 to 12 hrs by Western blot analysis relative to control
Inhibition of AKT phosphorylation in human THP-1 cells incubated for 1 to 12 hrs by Western blot analysis relative to control
Inhibition of AKT phosphorylation in human Jurkat cells at 1 uM incubated for 1 to 12 hrs by Western blot analysis relative to control
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of AKT phosphorylation in human THP-1 cells at 1 uM incubated for 1 to 12 hrs by Western blot analysis relative to control
Inhibition of AKT phosphorylation in human MV4-11 cells incubated for 4 hrs by Western blot analysis
Inhibition of Akt3 (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of AKT phosphorylation at Ser473 in human LN-18 cells by Western blot analysis
Assay data:2 Tested
Inhibition of AKT phosphorylation at Thr308 in human LN-18 cells by Western blot analysis
Inhibition of pAKT level in patient-derived CRC organoid MCC19990-013 harboring KRAS G12A mutation at 1 uM measured after 24 hrs by immunoblot analysis
Assay data:2 Active, 2 Tested
Inhibition of AKT (unknown origin) by by FRET based Z'-LYTE assay
Inhibition of AKT (unknown origin)
Inhibition of Akt phosphorylation in human HCT-116 cells
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