BioAssay by Target (List) for Gene (Select 140609) - PubChem BioAssay - NCBI

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Select item 19629411.

NEK7 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1962941

Summary Related BioAssays by Target

Select item 19628372.

NEK7 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1962837

Summary Related BioAssays by Target

Select item 19627453.

NEK7 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1962745

Summary Related BioAssays by Target

Select item 19626464.

NEK7 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1962646

Summary Related BioAssays by Target

Select item 19557385.

Inhibition of Nek7 (unknown origin)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1955738

Summary Related BioAssays by Target

Select item 19488866.

Inhibition of NEK7 (unknown origin) at 3 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1948886

Summary Related BioAssays by Target

Select item 19488777.

Inhibition of NEK7 (unknown origin) at 100 nM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:2 Tested

AID:: 1948877

Summary Related BioAssays by Target

Select item 19488488.

Inhibition of NEK7 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:42 Tested

AID:: 1948848

Summary Related BioAssays by Target

Select item 19488379.

Inhibition of NEK7 (unknown origin) at 10 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:10 Tested

AID:: 1948837

Summary Related BioAssays by Target

Select item 194882810.

Inhibition of NEK7 (unknown origin) assessed as dissociation constant

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1948828

Summary Related BioAssays by Target

Select item 191961211.

NEK7 Enzymatic Assay from US Patent US11713321: "Inhibitors of NEK7 kinase"

Source:: BindingDB

Protein Targets:: Serine/threonine-protein kinase Nek7; ...
Total:: 1

Assay data:27 Active, 27 Activity ≤ 1 µM, 44 Tested

AID:: 1919612

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191445412.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000289c NEK7

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1914454

Summary Related BioAssays by Target

Select item 191445313.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000289c NEK7

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1914453

Summary Related BioAssays by Target

Select item 191426814.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000724a NEK7

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1914268

Summary Related BioAssays by Target

Select item 191257715.

Thermal Shift Assay. Domain: start/stop: N29-S302

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:27 Tested

AID:: 1912577

Summary Related BioAssays by Target

Select item 190153616.

Inhibition of recombinant human NEK7 (2 to end residues) assessed as residual activity at 1 uM using FLAKSFGSPNRAYKK as substrate measured after 40 mins in presence of [gamma33P]ATP by radiometric scintillation counting method relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1901536

Summary PubMed Citation Related BioAssays by Target

Select item 183549217.

NEK7 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1835492

Summary Related BioAssays by Target

Select item 183530018.

NEK7 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1835300

Summary Related BioAssays by Target

Select item 183507619.

NEK7(h) Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1835076

Summary Related BioAssays by Target

Select item 183424720.

Inhibition of NEK7 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek7

Assay data:1 Tested

AID:: 1834247

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (3)
BioAssays with protein sequences specified as targets
RNAi Target, Active (9)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (20)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (6)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (20)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (42)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (159)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (46)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (124)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (78)
BioAssays deposited by other experimentalists

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