BioAssay by Target (List) for Gene (Select 1453) - PubChem BioAssay - NCBI

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Select item 19628891.

CSNK1D SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Tested

AID:: 1962889

Summary Related BioAssays by Target

Select item 19627852.

CSNK1D SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Tested

AID:: 1962785

Summary Related BioAssays by Target

Select item 19626993.

CSNK1D SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Tested

AID:: 1962699

Summary Related BioAssays by Target

Select item 19626004.

CSNK1D SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Tested

AID:: 1962600

Summary Related BioAssays by Target

Select item 19490195.

Inhibition of CK1D (unknown origin) by Ambit kinase assay

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:2 Tested

AID:: 1949019

Summary PubMed Citation Related BioAssays by Target

Select item 19408656.

Inhibition of CHKdelta (unknown origin)

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:2 Activity ≤ 1 µM, 2 Tested

AID:: 1940865

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19243447.

Inhibition of CK1 (unknown origin)

Source:: ChEMBL

Protein Targets:: Casein kinase I isoform alpha; ...
Total:: 5

Assay data:2 Active, 1 Activity ≤ 1 µM, 7 Tested

AID:: 1924344

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19200128.

CSNK1D Assay from US Patent US20230365554: "SUBSTITUTED PYRROLO-PYRIDINONE DERIVATIVES AND THERAPEUTIC USES THEREOF"

Source:: BindingDB

Protein Targets:: Casein kinase I isoform delta; ...
Total:: 1

Assay data:32 Active, 32 Activity ≤ 1 µM, 32 Tested

AID:: 1920012

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19199269.

CSNK1D-Inhibitory Activity Assay from US Patent US20230339939: "SUBSTITUTED 1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS AND METHODS OF USE THEREOF"

Source:: BindingDB

Protein Targets:: Casein kinase I isoform delta; ...
Total:: 1

Assay data:44 Active, 44 Activity ≤ 1 µM, 44 Tested

AID:: 1919926

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191992310.

Enzyme Assay from US Patent US20230339900: "CASEIN KINASE 1 DELTA MODULATORS"

Source:: BindingDB

Protein Targets:: Casein kinase I isoform delta; ...
Total:: 1

Assay data:132 Active, 91 Activity ≤ 1 µM, 153 Tested

AID:: 1919923

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191984811.

CSNK1D Assay from US Patent US20230322767: "ARYL SUBSTITUTED PYRROLO-PYRIDINONES AND THERAPEUTIC USES THEREOF"

Source:: BindingDB

Protein Targets:: Casein kinase I isoform delta; ...
Total:: 1

Assay data:131 Active, 131 Activity ≤ 1 µM, 131 Tested

AID:: 1919848

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191974112.

No assay from US Patent US11759530: "TKI permeability enhancers"

Source:: BindingDB

Protein Targets:: Activin receptor type-1B; ...
Total:: 22

Assay data:9 Active, 9 Activity ≤ 1 µM, 11 Tested

AID:: 1919741

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191414813.

Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000718a CSNK1D

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Tested

AID:: 1914148

Summary Related BioAssays by Target

Select item 191414714.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000718a CSNK1D

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Tested

AID:: 1914147

Summary Related BioAssays by Target

Select item 191251915.

Thermal Shift Assay. Domain: start/stop: M1-K294

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:26 Tested

AID:: 1912519

Summary Related BioAssays by Target

Select item 189996316.

Inhibition of human CK-1-delta at 10 uM by radiometric kinase activity assay relative to control

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Tested

AID:: 1899963

Summary PubMed Citation Related BioAssays by Target

Select item 189996217.

Inhibition of human CK-1-delta at 0.1 uM by radiometric kinase activity assay relative to control

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Tested

AID:: 1899962

Summary PubMed Citation Related BioAssays by Target

Select item 189931518.

Binding affinity to CK1delta (unknown origin)

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1899315

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189831519.

Inhibition of CK1 (unknown origin) assessed as residual activity at 30 uM relative to control

Source:: ChEMBL

Protein Targets:: Casein kinase I isoform alpha; ...
Total:: 5

Assay data:1 Tested

AID:: 1898315

Summary PubMed Citation Related BioAssays by Target

Select item 188823120.

Inhibition of CSNK1D (unknown origin) at 1 uM incubated in presence of ATP by Selectscreen kinase assay relative to control

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:2 Tested

AID:: 1888231

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets
RNAi Target, Active (9)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (113)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (3)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (90)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (145)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (41)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (1,379)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (45)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (399)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (1,022)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 1453) (1424)
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ClinVar for Gene (Select 1453) (44)
ClinVar
PREDICTED: Homo sapiens casein kinase 1 delta (CSNK1D), transcript variant X3, m...
PREDICTED: Homo sapiens casein kinase 1 delta (CSNK1D), transcript variant X3, mRNA
gi|2217310044|ref|XM_047435380.1|

Nucleotide

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