Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of adrenergic alpha-2C receptor (unknown origin) at 10 uM relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Antagonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as inhibition of UK14304-induced cytoplasmic calcium mobilization at 20 uM preincubated for 15 mins by fluorometric analysis relative to control
Assay data:3 Tested
Inhibition of alpha-2C adrenergic receptor (unknown origin)
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at human Alpha-2C adrenoceptor expressed in CHO cells assessed as induction of extracellular acidification by microphysiometry
Assay data:19 Active, 18 Activity ≤ 1 µM, 19 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Displacement of [125I]HEAT from adrenergic Alpha-2C receptor at 10 uM
Alpha-2C adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP; NA=not active
Agonistic activity towards human Alpha-2C adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine monophosphate
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Compound was evaluated for inhibition of binding of [3H]MK-91 to Alpha-2 adrenergic receptor in opossum kidney
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement in human platelet membranes
Assay data:1 Active, 1 Tested
Adrenoceptor blockade property was evaluated on vascular Alpha-1 adrenergic receptor
Compound was evaluated for the displacement of [3H]yohimbine in acetonitrile/acetic acid anti-corynanthine MIPs for Alpha-2 adrenergic receptor
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on