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Safety47 Scan (DiscoverX - Eurofins)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Adrenergic beta1 Eurofins Panlabs panel
BETA1/HUM Eurofins SafetyScreen44 (BI)
Compound was evaluated for inhibition of human ADRB1 in an in vitro assay measured by radioactivity method
Assay data:66 Active, 1 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 1195 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at human ADRB1 in an in vitro cell-based assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:81 Tested
SummaryPubMed CitationRelated BioAssays by Target
Displacement of [3H](-)CGP 12177 from human beta1 adrenoceptor at 10 uM after 60 mins by scintillation counting analysis relative to control
Assay data:3 Tested
Agonist activity at human adrenergic receptor expressed in CHO cells
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Agonist activity at human adrenergic receptor expressed in CHO cells assessed as intrinsic activity
Assay data:2 Tested
Inhibition of beta1 adrenergic receptor (unknown origin) at 10 uM
Selectivity interaction (Eurofins-Panlabs panel (at Boehringer Ingelheim)) EUB0000314b ADRB1
Selectivity interaction (GPCR panel (PDSP screen)) EUB0000352a ADRB1
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Selectivity interaction (GPCR panel (PDSP screen)) EUB0000735a ADRB1
Selectivity interaction (Enzyme panel (Eurofins-Panlabs radioligand binding assays)) EUB0000313b ADRB1
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