BioAssay by Target (List) for Gene (Select 1890) - PubChem BioAssay - NCBI

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Select item 2429041.

Vmax against human thymidine phosphorylase

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Tested

AID:: 242904

Summary PubMed Citation Related BioAssays by Target

Select item 2133072.

Inhibition of Escherichia coli TPase at a concentration of 25 uM after 60 minutes

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:2 Tested

AID:: 213307

Summary PubMed Citation Related BioAssays by Target

Select item 2133083.

Inhibition of Escherichia coli TPase at a concentration of 500 uM after 20 minutes

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Tested

AID:: 213308

Summary PubMed Citation Related BioAssays by Target

Select item 2133094.

Inhibition of Escherichia coli TPase at a concentration of 500 uM after 40 minutes

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Tested

AID:: 213309

Summary PubMed Citation Related BioAssays by Target

Select item 2133105.

Inhibition of Escherichia coli TPase at a concentration of 500 uM after 60 minutes

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Tested

AID:: 213310

Summary PubMed Citation Related BioAssays by Target

Select item 2133116.

Inhibition of Escherichia coli Thymidine Phosphorylase at a concentration of 100 uM after 20 minutes

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:9 Tested

AID:: 213311

Summary PubMed Citation Related BioAssays by Target

Select item 2133127.

Inhibition of Escherichia coli Thymidine Phosphorylase at a concentration of 100 uM after 40 minutes

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:9 Tested

AID:: 213312

Summary PubMed Citation Related BioAssays by Target

Select item 2133138.

Inhibition of Escherichia coli Thymidine Phosphorylase at a concentration of 100 uM after 60 minutes

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:11 Tested

AID:: 213313

Summary PubMed Citation Related BioAssays by Target

Select item 2133179.

Inhibition selectivity ratio against Thymidine Phosphorylase is the ratio of IC50 of the nitro compound to the IC50 of amino compound

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:3 Tested

AID:: 213317

Summary PubMed Citation Related BioAssays by Target

Select item 23836110.

Inhibitory activity against thymidine phosphorylase

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 238361

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 23974111.

Michaelis-Menten constant against human thymidine phosphorylase

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Tested

AID:: 239741

Summary PubMed Citation Related BioAssays by Target

Select item 24106112.

Inhibitory concentration against human thymidine phosphorylase

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:5 Active, 4 Activity ≤ 1 µM, 14 Tested

AID:: 241061

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 24137213.

Inhibitory concentration against horse liver thymidine phosphorylase of horse liver

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Tested

AID:: 241372

Summary PubMed Citation Related BioAssays by Target

Select item 24153914.

Inhibitory concentration against human thymidine phosphorylase

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Tested

AID:: 241539

Summary PubMed Citation Related BioAssays by Target

Select item 21330615.

Inhibition of Escherichia coli TPase at a concentration of 20 uM after 60 minutes

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:2 Tested

AID:: 213306

Summary PubMed Citation Related BioAssays by Target

Select item 24291516.

Catalytic constant against human thymidine phosphorylase

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Tested

AID:: 242915

Summary PubMed Citation Related BioAssays by Target

Select item 24305417.

Ratio of Kcat to Km against human thymidine phosphorylase

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:1 Tested

AID:: 243054

Summary PubMed Citation Related BioAssays by Target

Select item 26161118.

Inhibition of human TP expressed in V79 cells

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:20 Active, 23 Tested

AID:: 261611

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 26161219.

Inhibition of human TP purified from placenta

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:22 Active, 23 Tested

AID:: 261612

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 27012820.

Inhibition of human TPase in presence of 100 uM thymidine

Source:: ChEMBL

Protein Target:: Thymidine phosphorylase

Assay data:3 Active, 23 Tested

AID:: 270128

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (7)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (44)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (30)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (59)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (10)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (96)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (14)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (96)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (13)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 1890) (110)
PubChem BioAssay
Adult acute myeloid leukemia: bone marrow and peripheral blood expression profil...
Adult acute myeloid leukemia: bone marrow and peripheral blood expression profiles (SHCO)
Accession: GDS841

GEO DataSets
Related DataSets for GEO Profiles (Select 7046241) (1)
GEO DataSets
GAP Links for Gene (Select 1890) (1)
dbGaP

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