BioAssay by Target (List) for Gene (Select 20133) - PubChem BioAssay - NCBI

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Links from Gene

Items: 19

Select item 1981451.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 35-40

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198145

Summary PubMed Citation Related BioAssays by Target

Select item 1979842.

Cross inhibitory potency of compound on Saccharomyces cerevisiae R2 C-terminal peptide on Saccharomyces cerevisiae ribonucleotide reductase

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:3 Tested

AID:: 197984

Summary PubMed Citation Related BioAssays by Target

Select item 1981363.

Cross inhibitory potency of compound on Saccharomyces cerevisiae R2 C-terminal peptide on Saccharomyces cerevisiae ribonucleotide reductase

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198136

Summary PubMed Citation Related BioAssays by Target

Select item 1981374.

Cross inhibitory potency of compound on Saccharomyces cerevisiae R2 C-terminal peptide on mammalian ribonucleotide reductase

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:2 Tested

AID:: 198137

Summary PubMed Citation Related BioAssays by Target

Select item 1981395.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 110-230

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198139

Summary PubMed Citation Related BioAssays by Target

Select item 1981406.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 25-29

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198140

Summary PubMed Citation Related BioAssays by Target

Select item 1981417.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 286-336

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198141

Summary PubMed Citation Related BioAssays by Target

Select item 1981428.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 29-30

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198142

Summary PubMed Citation Related BioAssays by Target

Select item 1981439.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 32-38

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198143

Summary PubMed Citation Related BioAssays by Target

Select item 19814410.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 34-35

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198144

Summary PubMed Citation Related BioAssays by Target

Select item 122482811.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout

Source:: Iain Fraser

Assay data:762 Active, 16821 Tested

AID:: 1224828

Summary Related BioAssays by Same Project

Select item 19814612.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 364-460

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198146

Summary PubMed Citation Related BioAssays by Target

Select item 19814713.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 40-42

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198147

Summary PubMed Citation Related BioAssays by Target

Select item 19814814.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 450-620

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198148

Summary PubMed Citation Related BioAssays by Target

Select item 19826415.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 48-58

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Tested

AID:: 198264

Summary PubMed Citation Related BioAssays by Target

Select item 19826516.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 8-20

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:2 Active, 2 Tested

AID:: 198265

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19826617.

Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 9-15

Source:: ChEMBL

Protein Target:: Ribonucleoside-diphosphate reductase large subunit

Assay data:1 Active, 1 Tested

AID:: 198266

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 105320818.

A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:788 Active, 16789 Tested

AID:: 1053208

Summary PubMed Citation

Select item 122482619.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout

Source:: Iain Fraser

Assay data:1106 Active, 16821 Tested

AID:: 1224826

Summary Related BioAssays by Same Project

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BioActivity

Active Compounds (2)
BioAssays with compounds reported as biologically active

Experiment Type

Summary (2)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (16)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (16)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (3)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (16)
BioAssays extracted from the literature
Other (3)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 20133) (19)
PubChem BioAssay
GEO Profiles Links for Nucleotide (Select 26105702) (146)
GEO Profiles
Mus musculus
Mus musculus
RefSeq annotation of the mouse reference genome assembly.

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BioProject Links for Nucleotide (Select 1907135931) (1)
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PubChem Compound Links for Gene (Select 57905) (17)
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