BioAssay by Target (List) for Gene (Select 2028) - PubChem BioAssay - NCBI

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Select item 7434541.

RNAi screen for vorinostat resistance genes - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:450 Active, 18118 Tested

AID:: 743454

Summary PubMed Citation

Select item 19042.

siRNA Circadian Assay

Source:: The Genomics Institute of the Novartis Research Foundation (GNF)

Assay data:527 Active, 33364 Tested

AID:: 1904

Summary PubMed Citation Related BioAssays by Depositor

Select item 356983.

Inhibition of aminopeptidase A (APA) at 0.4 mM

Source:: ChEMBL

Protein Target:: Glutamyl aminopeptidase

Assay data:4 Tested

AID:: 35698

Summary PubMed Citation Related BioAssays by Target

Select item 356994.

Inhibition of aminopeptidase A (APA)

Source:: ChEMBL

Protein Target:: Glutamyl aminopeptidase

Assay data:11 Active, 3 Activity ≤ 1 µM, 13 Tested

AID:: 35699

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 357005.

Inhibition of aminopeptidase A (APA)

Source:: ChEMBL

Protein Target:: Glutamyl aminopeptidase

Assay data:14 Active, 9 Activity ≤ 1 µM, 14 Tested

AID:: 35700

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 357016.

Binding affinity against recombinant Aminopeptidase A

Source:: ChEMBL

Protein Target:: Glutamyl aminopeptidase

Assay data:33 Active, 1 Activity ≤ 1 nM, 31 Activity ≤ 1 µM, 33 Tested

AID:: 35701

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4456167.

Inhibition of APA at 10 uM

Source:: ChEMBL

Protein Target:: Glutamyl aminopeptidase

Assay data:1 Tested

AID:: 445616

Summary PubMed Citation Related BioAssays by Target

Select item 6240998.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 6518109.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 65181110.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

Select item 74312111.

Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:167 Active, 26449 Tested

AID:: 743121

Select item 153741712.

Stability in pH 2 HCl assessed as aminopeptidase (unknown origin)-mediated compound hydrolysis by measuring parent compound remaining at 200 uM up to 6 hrs by RP-HPLC analysis

Source:: ChEMBL

Protein Targets:: Aminopeptidase B; ...
Total:: 19

Assay data:1 Tested

AID:: 1537417

Summary PubMed Citation Related BioAssays by Target

Select item 111728113.

A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:555 Active, 64752 Tested

AID:: 1117281

Summary PubMed Citation

Select item 111735714.

InfectX: Pathogen infection siRNA screens

Source:: InfectX Consortium

Assay data:115372 Tested

AID:: 1117357

Summary PubMed Citation

Select item 115950615.

Identification of proteins required for the processing of the EWS-FLI1 nascent transcript

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:59220 Tested

AID:: 1159506

Select item 115957816.

A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:1034 Active, 18120 Tested

AID:: 1159578

Summary Related BioAssays by Depositor

Select item 115958417.

A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:2442 Active, 18052 Tested

AID:: 1159584

Summary PubMed Citation

Select item 122483018.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout

Source:: Iain Fraser

Assay data:2853 Active, 18113 Tested

AID:: 1224830

Summary Related BioAssays by Same Project

Select item 138037419.

Inhibition of APA (unknown origin) using GlubetaNA as substrate after 30 mins

Source:: ChEMBL

Protein Target:: Glutamyl aminopeptidase

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1380374

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 138038420.

Inhibition of APA (unknown origin)

Source:: ChEMBL

Protein Target:: Glutamyl aminopeptidase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1380384

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (6)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (6)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (6)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (9)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (9)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (12)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 2028) (22)
PubChem BioAssay
Interleukin 4, interleukin 13 and tumor necrosis factor-α effect on plastic-cult...
Interleukin 4, interleukin 13 and tumor necrosis factor-α effect on plastic-cultured IMR-90 lung fibroblast cells
Accession: GDS5262

GEO DataSets
Related DataSets for GEO Profiles (Select 119581641) (1)
GEO DataSets
glutamyl aminopeptidase isoform X1 [Homo sapiens]
glutamyl aminopeptidase isoform X1 [Homo sapiens]
gi|2462595465|ref|XP_054205159.1|

Protein

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