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Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000143b EPHB2
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of wild-type human partial length EPHB2 (I597 to L902 residues) expressed in bacterial expression system at 1 uM by Kinomescan method relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of EPHB2 (unknown origin) at 100 nM relative to control
Displacement of biotinylated ephrin-B1-Fc from EphB2 (unknown origin) preincubated for 1 hr followed by biotinylated-ephrin-B1-Fc addition measured after 4 hrs by ELISA
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of EPHB2 assessed as enzyme activity at 1 uM relative to untreated control
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