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Inhibition of SIRT5 (unknown origin) at 100 uM relative to control
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of SIRT5 (unknown origin) at 30 uM relative to control
Inhibition of SIRT5 (unknown origin) at 10 uM relative to control
Inhibition of SIRT5 (unknown origin)
Assay data:2 Tested
Inhibition of SIRT5 (unknown origin) assessed as activity at 312.5 uM relative to control
Activation of SIRT5 (unknown origin) assessed as fold increase in deacetylase activity at 200 uM relative to control
SummaryPubMed CitationRelated BioAssays by Target
Activation of SIRT5 (unknown origin) assessed as fold increase in deacetylase activity at 50 uM relative to control
Activation of SIRT5 (unknown origin) assessed as fold increase in deacetylase activity at 10 uM relative to control
Inhibition of SIRT5 (unknown origin) desuccinylation activity
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of NAD+ dependent SIRT5 (unknown origin) using chicken histone as substrate
Inhibition of SIRT5 (unknown origin) at 50 uM incubated for 15 mins by fluorometric assay relative to control
Inhibition of SIRT5 desuccinylase activity (unknown origin) using succinyl-lysine as substrate
Assay data:3 Active, 4 Tested
Inhibition of GST-tagged SIRT5 desuccinylase activity (unknown origin) incubated for 5 mins by HPLC based assay
Assay data:2 Active, 2 Tested
Inhibition of SIRT5 activity (unknown origin)
Inhibition of SIRT5 de-glutarylase activity (unknown origin) at 100 uM relative to control
Inhibition of human recombinant SIRT5 using fluorogenic Benzyl-Lys(Succinyl)-AMC as substrate incubated for 2 hrs measured by fluoroscence based microplate reader method
Assay data:3 Active, 10 Tested
Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constant
Assay data:5 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of SIRT5 deglutarylase activity (unknown origin)
Assay data:7 Active, 9 Activity ≤ 1 µM, 9 Tested
Inhibition of SIRT5 desuccinylase activity (unknown origin)
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Binding affinity to SIRT5 (unknown origin) assessed as desuccinylation activity by measuring inhibition constant
Assay data:1 Active, 5 Tested
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