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Inhibition of Aryl hydrocarbon hydroxylase in phenobarbitone-treated rats
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 1.2x10E-3M
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 1.7x10E-4M
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 2.3x10E-4M
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 3.6x10E-4M
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 4.3x10E-4M
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 5.0x10E-5M
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 5.2x10E-5M
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 5.9x10E-4M
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 8x10E-4M
Effect on Aryl hydrocarbon hydroxylase activity in 3-methylcolanthrene-induced rat liver microsomes at 2.6x10E-4M
Assay data:13 Tested
Assay data:8 Tested
Induction of CYP1A1 in rat hepatocytes at 0.1 to 10 uM incubated for 48 hrs
Spectral dissociation constant for rat liver Cytochrome P450 1A1
Interaction with cytochrome P450 in 3-methylcholanthrene-induced rat hepatic microsomes
Assay data:1 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Interaction (Ks) with cytochrome P450 in 3-methylcholanthrene-induced rat hepatic microsomes
Assay data:2 Tested
Mechanism based inhibition of rat cytochrome P450 CYP1A1
Mechanism based inhibition of rat cytochrome P450 CYP1A1 measured by 7-ethoxyresorufin O-deethylation (EROD)
Assay data:9 Active, 8 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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