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Effect on rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as decrease in channel mean open time by outside patch clamp technique relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 300 uM glycine-elicited current at 3 uM by outside patch clamp technique
Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 300 uM glycine-elicited current by outside patch clamp technique
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 30 uM glycine-elicited current at 10 uM by outside patch clamp technique
Assay data:1 Tested
Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 300 uM glycine-elicited current at 10 uM by outside patch clamp technique
Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 30 uM glycine-elicited current at 300 uM by outside patch clamp technique
Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 300 uM glycine-elicited current at 3 uM at +50 mV voltage by outside patch clamp technique
Assay data:1 Active, 1 Tested
Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 300 uM glycine-elicited current at 100 uM at +50 mV voltage by outside patch clamp technique
Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 300 uM glycine-elicited current at 100 uM at -50 mV voltage by outside patch clamp technique
Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of deactivation time constant by outside patch clamp technique
Effect on rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as shortened single receptor burst opening in response to glycine-pulse at 10 uM by outside patch clamp technique
Effect on rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as shortened single receptor burst opening in response to glycine-pulse at 30 uM by outside patch clamp technique
Effect on rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as flickering of channel in response to glycine-pulse at 30 uM by outside patch clamp technique
Effect on rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as decrease in channel mean open time at 10 uM by outside patch clamp technique relative to control
Effect on rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as decrease in channel mean open time at 30 uM by outside patch clamp technique relative to control
Displacement of [3H]strychnine from glycine ion channel in Wistar rat spinal cord membranes at 10 uM incubated for 10 mins by radiometric scintillation analysis relative to control
Effect on rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as decrease in activation phase of glycine response at 10 uM by outside patch clamp technique
Effect on rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as decrease in activation phase of glycine response at 30 uM by outside patch clamp technique
Effect on rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as change in rising time constant of glycine response at 10 uM by outside patch clamp technique
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