BioAssay by Target (List) for Gene (Select 2555) - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

Items: 1 to 20 of 370

<< First< Prev

Page of 19

Select item 19632461.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-3; ...
Total:: 16

Assay data:1 Tested

AID:: 1963246

Summary Related BioAssays by Target

Select item 19632452.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-2; ...
Total:: 16

Assay data:1 Tested

AID:: 1963245

Summary Related BioAssays by Target

Select item 19632443.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1963244

Summary Related BioAssays by Target

Select item 19631984.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1963198

Summary Related BioAssays by Target

Select item 19631975.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-2; ...
Total:: 16

Assay data:1 Tested

AID:: 1963197

Summary Related BioAssays by Target

Select item 19631966.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-5; ...
Total:: 16

Assay data:1 Tested

AID:: 1963196

Summary Related BioAssays by Target

Select item 19617567.

Binding affinity towards human GABRA1 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 4

Assay data:1 Active, 3 Activity ≤ 1 µM, 438 Tested

AID:: 1961756

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19617548.

Antagonist activity at human GABRA1 in an in vitro cell-based assay measured by fluorescent imaging plate reader

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 4

Assay data:2 Active, 297 Tested

AID:: 1961754

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19617539.

Agonist activity at human GABRA1 in an in vitro cell-based assay measured by fluorescent imaging plate reader

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 4

Assay data:2 Active, 293 Tested

AID:: 1961753

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 196124810.

Inhibition of GABAA receptor (unknown origin) upto 10000 nM

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1961248

Summary PubMed Citation Related BioAssays by Target

Select item 195970111.

Positive allosteric modulation of human GABAA alpha2beta1gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assay

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-2; ...
Total:: 3

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1959701

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 195968412.

Potentiation of NAS mediated GABA (unknown origin) tonic effect assessed as fold potentiation

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:6 Tested

AID:: 1959684

Summary PubMed Citation Related BioAssays by Target

Select item 194133713.

Positive allosteric modulator activity at human GABAA receptor measured by [35S]TBPS based functional assay

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1941337

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194070214.

Inhibition of GABAA receptor (unknown origin) at 50 uM by radioligand receptor binding assay relative to control

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:23 Tested

AID:: 1940702

Summary PubMed Citation Related BioAssays by Target

Select item 193409615.

Inhibition of GABA-A alpha2 receptor (unknown origin) relative to control

Source:: ChEMBL

Protein Target:: Gamma-aminobutyric acid receptor subunit alpha-2

Assay data:2 Tested

AID:: 1934096

Summary PubMed Citation Related BioAssays by Target

Select item 193409416.

Inhibition of GABA-A receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1934094

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193230717.

Inhibition of GABAA alpha2 receptor (unknown origin)

Source:: ChEMBL

Protein Target:: Gamma-aminobutyric acid receptor subunit alpha-2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1932307

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193230518.

Inhibition of GABAA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:9 Active, 4 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 10 Tested

AID:: 1932305

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193229819.

Inhibition of human recombinant GABAA alpha2 receptor

Source:: ChEMBL

Protein Target:: Gamma-aminobutyric acid receptor subunit alpha-2

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1932298

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193229220.

Binding affinity to human recombinant GABAA alpha2 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting analysis

Source:: ChEMBL

Protein Target:: Gamma-aminobutyric acid receptor subunit alpha-2

Assay data:21 Active, 3 Activity ≤ 1 nM, 21 Activity ≤ 1 µM, 21 Tested

AID:: 1932292

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

<< First< Prev

Page of 19

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (149)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (32)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (127)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (186)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (357)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (334)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (35)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Recent activity

Clear Turn Off Turn On

BioAssay by Target (List) for Gene (Select 2555) (370)
PubChem BioAssay
Taxonomy Links for GEO Profiles (Select 58882128) (1)
Taxonomy
KIF2C kinesin family member 2C [Homo sapiens]
KIF2C kinesin family member 2C [Homo sapiens]
Gene ID:11004

Gene
Gene Links for GEO Profiles (Select 105197546) (1)
Gene
MRPL36 mitochondrial ribosomal protein L36 [Homo sapiens]
MRPL36 mitochondrial ribosomal protein L36 [Homo sapiens]
Gene ID:64979

Gene

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay