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Inhibition of MYOF in human PANC1 cells assessed as increase in EGF-stimulated EGFR phosphorylation by Western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MYOF in human PANC1 cells assessed as reduction in VEGFR2 level by Western blot analysis
Inhibition of MYOF in human PANC1 cells assessed as reduction in phospho-VEGFR2 level by Western blot analysis
Inhibition of MYOF in human PANC1 cells assessed as reduction in MMP2 secretion measured after 24 hrs by SDS-PAGE analysis
Inhibition of MYOF in human PANC1 cells assessed as reduction in MMP1 secretion measured after 24 hrs by SDS-PAGE analysis
Inhibition of MYOF in human PANC1 cells assessed as reversal of epithelial-mesenchymal transition by measuring down regulation of fibronectin expression up to 400 nM by Western blot analysis
Inhibition of MYOF in human PANC1 cells assessed as reversal of epithelial-mesenchymal transition by measuring up regulation of E-cadherin expression up to 400 nM by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to recombinant human GST-tagged MYOF C2 domain (3445 to 3912 residues) expressed in Escherichia coli BL21 (DE3) at 145 uM by STD-NMR analysis
Binding affinity to recombinant human GST-tagged MYOF C2 domain (3445 to 3912 residues) expressed in Escherichia coli BL21 (DE3) at 0.03125 to 0.5 uM by surface plasmon resonance analysis
Binding affinity to recombinant human GST-tagged MYOF C2 domain (3445 to 3912 residues) expressed in Escherichia coli BL21 (DE3) at 0.3125 to 10 uM by surface plasmon resonance analysis
Reversible binding affinity to recombinant human GST-tagged MYOF C2 domain (3445 to 3912 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
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