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InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
SummaryPubMed Citation
Binding affinity to RGS17 (unknown origin) assessed as change in melting temperature by differential scanning fluorimetry
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of wild type GST-tagged RGS17 (unknown origin) interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScreen assay
Binding affinity to RGS17 (unknown origin) by ITC method
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of RGS17 (unknown origin) GAP activity in presence of GTP by malachite green dye based assay
Assay data:2 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
Inhibition of RGS17 (unknown origin) C117A mutant interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScreen assay
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Inhibition of cell membrane translocation of N-terminal GFP tagged and N-terminal deficient RGS17 (unknown origin) expressed in HEK293T cells co-expressing Galpha-o assessed as induction of delocalization of RGS17deltaN to cytoplasm at 10 uM incubated for 10 mins by confocal microscopy
Assay data:3 Active, 3 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Binding affinity to RGS17 (unknown origin) assessed as covalent adduct formation at 100 uM after 72 hrs by ESI-MS analysis
Assay data:1 Active, 3 Tested
Binding affinity to RGS17 (unknown origin) assessed as change in chemical shift perturbations by NMR spectroscopic analysis
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