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I1 CEREP ligand profiling
Assay data:1 Tested
SummaryRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Binding affinity to Galphai1 (unknown origin) coupled with alpha-2 adrenoceptor transfected in HEK293 GloSensor cells assessed as restoration of Fsk/UK14304-induced reduction of cAMP preincubated for 20 mins followed by Fsk/UK14304 induction measured every 2 secs by FLIPR assay
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to Galphai1 (unknown origin) coupled with alpha-2 adrenoceptor transfected in HEK293 GloSensor cells assessed as restoration of Fsk/UK14304-induced reduction of cAMP at 0.1 to 10 uM preincubated for 20 mins followed by Fsk/UK14304 induction measured every 2 secs by FLIPR assay
Binding affinity to Galphai1 (unknown origin) coupled with alpha-2 adrenoceptor transfected in HEK293 GloSensor cells assessed as restoration of Fsk/UK14304-induced reduction of cAMP at 100 nM preincubated for 20 mins followed by Fsk/UK14304 induction measured every 2 secs by FLIPR assay relative to control
Binding affinity to GDP-bound human Galphai1 expressed in Escherichia coli BL21 in H2O/DMSO-d6 at 500 uM by STD NMR analysis
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to human Galphai1 expressed in Escherichia coli BL21 assessed as inhibition of [35S]GTPgammaS binding preincubated for 20 mins followed by [35S]GTPgammaS addition measured for 30 mins by liquid scintillation counting analysis
Assay data:1 Active, 1 Tested
Binding affinity to human Galphai1 expressed in Escherichia coli BL21 assessed as inhibition of BODIPY FL GTPgammaS binding by measuring fluorescence reduction at 30 to 300 uM preincubated for 30 mins followed by BODIPY FL GTPgammaS addition measured for 60 mins by real time nucleotide exchange assay relative to vehicle-treated control
Assay data:34 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Inhibition of Galphai-mediated LPA-stimulated cell invasion in human SKOV3 cells
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