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Inhibition of human full-length recombinant SENP1
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human SENP1 catalytic domain assessed as reduction in deSUMOylation of RanGAP1-SUMO2 using RanGAP1-SUMO2 as substrate by fluorescence based analysis
Assay data:2 Active, 3 Tested
Inhibition of human SENP1
Assay data:1 Active, 2 Tested
Inhibition of human recombinant His6 tagged SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO3-AMC as substrate incubated for 15 mins followed by substrate addition by fluorescence based analysis
Assay data:1 Active, 3 Tested
Inhibition of human recombinant His6 tagged SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO2-AMC as substrate incubated for 15 mins followed by substrate addition by fluorescence based analysis
Inhibition of human recombinant His6 tagged SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO1-AMC as substrate incubated for 15 mins followed by substrate addition by fluorescence based analysis
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO1-AMC as substrate incubated for 10 mins followed by substrate addition by fluorescence based analysis
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of SENP1 (unknown origin)
Assay data:12 Active, 16 Tested
Inhibition of recombinant human SENP1 catalytic domain using RanGAP1 as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by Western blot analysis
Assay data:3 Active, 1 Activity ≤ 1 µM, 4 Tested
Inhibition of recombinant human SENP1 catalytic domain at 2 uM using RanGAP1 as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by Western blot analysis relative to control
Assay data:54 Tested
Assay data:1 Tested
Inhibition of SENP1 (unknown origin) using AMC-tagged SUMO1 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by fluorescence assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of SENP1 in human SK-OV-3 cells assessed as increase in SUMOlytated JAK2 level at 5 uM after 48 hrs by immunoprecipitation method
Assay data:2 Active, 4 Tested
Inhibition of recombinant human SENP1 assessed as reduction in deSUMOylation using RanGAP1-SUMO1 as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins
Inhibition of recombinant human SENP1 assessed as reduction in deSUMOylation of RanGAP1-SUMO1 at 5 uM using RanGAP1-SUMO1 as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins relative to control
Assay data:20 Tested
Inhibition of SENP1 (unknown origin) assessed as reduction in deSUMOylation of RanGAP1-SUMO2 using RanGAP1-SUMO2 as substrate preincubated for 10 mins followed by substrate addition and measured after 45 mins by coomassie brilliant blue staining based SDS-PAGE analysis
Assay data:1 Active, 1 Tested
Inhibition of His-tagged human SENP1 (419 to 644 residues) expressed in Escherichia coli (DE3) using YFP-SUMO-ECFP as substrate incubated for 15 mins by Coomassie staining based SDS-PAGE analysis
Inhibition of human SENP1 using QTGG-AFC as substrate by fluorescence based analysis
Inhibition of human SENP1 using AMC-tagged SUMO1 as substrate incubated for 10 mins by fluorescence based analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
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