Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of human H-ras
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of HRAS (unknown origin) farnesylation
Inhibition of HRAS (unknown origin) transfected in BALB/c nude mouse incubated for 3 days measured by immunoblot analysis
Binding affinity to HRAS (unknown origin) assessed as inhibition constant
Inhibition of human p21 h-RAS assessed as reduction in C-Cdc25 stimulated nucleotide exchange by luminescence spectrometer based analysis
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Cellular assay: Active RAS (KRAS, HRAS, NRAS)in Calu-1 cells (KRASwt)
Assay data:1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Target
Cellular assay: Active RAS (KRAS, HRAS, NRAS) in HeLa cells (KRASwt)
SummaryRelated BioAssays by Target
Inhibition of GFP-tagged HRAS G12V mutant (unknown origin) expressed in MDCK cells assessed as reduction in ERK phosphorylation level incubated for 48 hrs by Western blot analysis
Assay data:1 Tested
Inhibition of GFP-tagged HRAS G12V mutant (unknown origin) expressed in MDCK cells assessed as reduction in Akt phosphorylation level incubated for 48 hrs by Western blot analysis
Inhibition of GFP-tagged HRAS G12V mutant (unknown origin) expressed in MDCK cells cotransfected with mCherry-CAXX assessed as effect on HRAS G12V-plasma membrane dissociation incubated for 48 hrs by quantitative confocal microscopic method
Binding affinity to NT-647 cysteine-labeled and N-terminal-GST-tagged recombinant human H-Ras (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) at up to 100 uM by microscale thermophoresis analysis
Assay data:3 Tested
Binding affinity to NT-647 cysteine-labeled and N-terminal-GST-tagged recombinant human H-Ras (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) at 0.006 to 100 uM by microscale thermophoresis analysis
Inhibition GST-tagged recombinant HRAS G12V mutant (1 to 166 amino acids) (unknown origin) expressed in Escherichia coli C41(DE3) by SPR assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of HRAS G12V mutant (unknown origin) expressed in mouse NIH/3T3 cells assessed as reduction in MAPK phosphorylation up to 100 nM measured after 2 hrs by Western blot analysis
Inhibition of HRAS G12V mutant (unknown origin) expressed in mouse NIH/3T3 cells assessed as reduction in cell proliferation up to 100 nM supplemented with fresh medium containing compound for every 2 to 3 days measured at 2 days interval during compound dosing
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Human HRAS (RAS subfamily)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on