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Selectivity interaction (Enzymatic assay) EUB0000609a INSRR
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Selectivity interaction (Ambit kinase binding assay panel) EUB0000609a INSRR
Assay data:1 Tested
SummaryRelated BioAssays by Target
Affinity Biochemical interaction (Radiometric kinase assay (100 M ATP)) EUB0000614a INSRR
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Affinity Phenotypic Cellular interaction (CellTiterGlo? luciferase-based cellular ATP assay (Promega; cell proliferation in SW620 cells)) EUB0000614a INSRR
INSRR DiscoveRx kinase panel
IRR(h) Kinase panel
Inhibition of IRR (unknown origin) at 1 uM
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant IRR assessed as reduction in substrate phosphorylation at 50 to 500 nM using ATP and Ulight-CKKSRGDYMTMQIG (IRS-1) incubated for 60 min by LANCE detection method
Inhibition of IRR (unknown origin) assessed as residual activity at 1 uM relative to control
Assay data:5 Tested
KinomeScan assay: inhibition of INSRR
Assay data:108 Tested
IRR(INSSLGF1) Takeda global kinase panel
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Target
IRR(h) Eurofins kinase panel
INSR-R ProQinase selectivity panel
INSRR (IRR) Kinase screen
INSRR Invitrogen selectivity data (BI)
IRR(h) Eurofins Kinase panel
IRR (h) Millipore kinase activity assay
IRR(h) Millipore kinase panel
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