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Inhibition of ABCC6 (unknown origin) expressed in HEK293 cells assessed as increase in doxorubicin efflux at 100 uM after 30 mins by fluorescence assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
TP_TRANSPORTER: inhibition of NEM-GS in the presence of Benzbromarone at a concentration of 30uM in membrane vesicles from MRP6-expressing Sf9 cells
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
TP_TRANSPORTER: inhibition of NEM-GS in the presence of Indomethacin at a concentration of 100uM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: inhibition of NEM-GS in the presence of Probenecid at a concentration of 1mM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: uptake in membrane vesicles from MRP6-expressing Sf9 cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
TP_TRANSPORTER: uptake in membrane vesicle from MRP6-expressing CHO cells
Assay data:3 Tested
TP_TRANSPORTER: inhibition of NEM-GS by Benzbromarone at a concentration of 30uM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: inhibition of NEM-GS by Indomethacin at a concentration of 100uM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: inhibition of NEM-GS by Probenecid at a concentration of 1mM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: drug resistance in MRP6-expressing CHO cells
Assay data:6 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
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