BioAssay by Target (List) for Gene (Select 3777) - PubChem BioAssay - NCBI

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Select item 11595061.

Identification of proteins required for the processing of the EWS-FLI1 nascent transcript

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:59220 Tested

AID:: 1159506

Select item 15255532.

Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assay

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:6 Active, 5 Activity ≤ 1 µM, 15 Tested

AID:: 1525553

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 15255523.

Inhibition of human TASK1 expressed in CHO cells by Inside-out macro-patches based electrophysiology assay

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1525552

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 15085884.

RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:790 Active, 18119 Tested

AID:: 1508588

Select item 13466025.

Human K2P3.1 (Two P domain potassium channels)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: potassium channel subfamily K member 3

Assay data:5 Active, 5 Tested

AID:: 1346602

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 13077346.

Inhibition of of TASK1 (unknown origin) expressed in CHO cells assessed as reduction in channel currents

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:1 Active, 2 Tested

AID:: 1307734

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 12248307.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout

Source:: Iain Fraser

Assay data:2853 Active, 18113 Tested

AID:: 1224830

Summary Related BioAssays by Same Project

Select item 11834538.

Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assay

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:8 Active, 7 Activity ≤ 1 µM, 8 Tested

AID:: 1183453

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 11834529.

Inhibition of TASK-1 (unknown origin) by parental cell based thallium flux assay

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1183452

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 118345110.

Inhibition of TASK-1 (unknown origin) at 3 uM by parental cell based thallium flux assay

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:1 Tested

AID:: 1183451

Summary PubMed Citation Related BioAssays by Target

Select item 118344511.

Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:52 Active, 1 Activity ≤ 1 nM, 50 Activity ≤ 1 µM, 58 Tested

AID:: 1183445

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 118344412.

Inhibition of TASK-1 (unknown origin) expressed in CHO cells at 3 uM by thallium flux assay

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:56 Tested

AID:: 1183444

Summary PubMed Citation Related BioAssays by Target

Select item 115958413.

A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:2442 Active, 18052 Tested

AID:: 1159584

Summary PubMed Citation

Select item 115957814.

A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:1034 Active, 18120 Tested

AID:: 1159578

Summary Related BioAssays by Depositor

Select item 152555515.

Inhibition of human TASK1 by whole cell voltage clamp assay

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1525555

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 111735716.

InfectX: Pathogen infection siRNA screens

Source:: InfectX Consortium

Assay data:115372 Tested

AID:: 1117357

Summary PubMed Citation

Select item 111728117.

A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:555 Active, 64752 Tested

AID:: 1117281

Summary PubMed Citation

Select item 74345418.

RNAi screen for vorinostat resistance genes - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:450 Active, 18118 Tested

AID:: 743454

Summary PubMed Citation

Select item 74312119.

Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:167 Active, 26449 Tested

AID:: 743121

Select item 72609120.

Inhibition of TASK-1 (unknown origin)

Source:: ChEMBL

Protein Target:: Potassium channel subfamily K member 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 726091

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (5)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (30)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (23)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (2)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (25)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (11)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (43)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (5)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (34)
BioAssays extracted from the literature
NIH MLP (5)
BioAssays deposited by the NIH Molecular Libraries Program
Other (17)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 3777) (56)
PubChem BioAssay
Taxonomy Links for Protein (Select 84488635) (1)
Taxonomy
Bangiaceae ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit (rbcL) ...
Bangiaceae ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit (rbcL) gene, partial cds; chloroplast.
PopSet: 942062213

PopSet
PopSet Links for Nucleotide (Select 942062481) (1)
PopSet
RPL10A ribosomal protein L10a [Homo sapiens]
RPL10A ribosomal protein L10a [Homo sapiens]
Gene ID:4736

Gene

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