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Inhibition of Maxi-K (unknown origin) expressed in HEK293 cells at 30 uM measured by thallium flux assay relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Maxi-K (unknown origin) expressed in HEK293 cells measured by thallium flux assay
Assay data:4 Tested
Activation of human BKca expressed in HEK293T cells at 10 uM by patch clamp electrophysiology method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activation of Maxi-K channel (unknown origin) by thallium flux assay
Assay data:1 Tested
Inhibition of human BK potassium channel expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay
Potentiation of human KCa1.1 expressed in HEK293 cells at 100 uM with -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology
SK+Ca channel CEREP ligand profiling
SummaryRelated BioAssays by Target
SKCa channel CEREP ligand profiling
K+ channel (Ca2+-dependent) CEREP ligand profiling
K+ channel (Ca2+ - dependent) Ligand binding assay
SK+ channel CEREP ligand profiling
Inhibition of BK calcium channel in human AD293 cells cells assessed as relative fluorescence unit at 1 to 30 uM in presence of 1 uM paxilline by cell-based fluorescence assay
Assay data:2 Active, 2 Tested
Inhibition of BK calcium channel in human AD293 cells assessed as relative fluorescence unit by cell-based fluorescence assay
Inhibition of BK calcium channel in human AD293 cells assessed as relative fluorescence unit at 5 uM by cell-based fluorescence assay relative to control
Assay data:27 Tested
Inhibition of human BK alpha/beta4 channel expressed in HEK293T cells assessed as inhibition of K+ outward current fraction at -80 mV holding potential by whole cell patch clamp technique
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human BK alpha/beta4 channel expressed in HEK293T cells assessed as K+ outward current fraction at 10 uM at -80 mV holding potential by whole cell patch clamp method relative to control
Assay data:7 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Human KCa1.1 (Calcium- and sodium-activated potassium channels)
Assay data:9 Active, 9 Tested
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