BioAssay by Target (List) for Gene (Select 3784) - PubChem BioAssay - NCBI

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Select item 19076081.

Inhibition of human KCNQ1 at 10 uM relative to control by Electrophysiological QPatch assay

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1907608

Summary PubMed Citation Related BioAssays by Target

Select item 18949032.

Agonist activity at human KCNQ1 channel expressed in CHO cells assessed as amplitude change of outward current at 10 uM by patch clamp method

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1894903

Summary PubMed Citation Related BioAssays by Target

Select item 18949023.

Agonist activity at human KCNQ1 channel expressed in CHO cells assessed as amplitude change of outward current at 0.1 uM by patch clamp method

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1894902

Summary PubMed Citation Related BioAssays by Target

Select item 18949014.

Agonist activity at human KCNQ1 channel expressed in CHO cells assessed as shift of half voltage of maximal activation at 10 uM by patch clamp method

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1894901

Summary PubMed Citation Related BioAssays by Target

Select item 18949005.

Agonist activity at human KCNQ1 channel expressed in CHO cells assessed as shift of half voltage of maximal activation at 0.1 uM by patch clamp method

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1894900

Summary PubMed Citation Related BioAssays by Target

Select item 18810636.

Inhibition of KCNQ1/MINK (unknown origin) by patch clamp method

Source:: ChEMBL

Protein Targets:: Misshapen-like kinase 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1881063

Summary PubMed Citation Related BioAssays by Target

Select item 18706237.

Agonist activity at human KCNQ1 channel expressed in CHO cells assessed as increase in outward current by patch clamp electrophysiology method

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1870623

Summary PubMed Citation Related BioAssays by Target

Select item 18699508.

Effect on human Kv7.1 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1869950

Summary PubMed Citation Related BioAssays by Target

Select item 18345469.

KvLQT1/minK Eurofins SafetyScreen (Other)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1834546

Summary Related BioAssays by Target

Select item 183183910.

Inhibition of human KCNQ1 at 10 uM

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1831839

Summary PubMed Citation Related BioAssays by Target

Select item 181558311.

Inhibition of human KCNQ1 at 30 uM comprehensive in-vitro proarrhythmia assay

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1815583

Summary PubMed Citation Related BioAssays by Target

Select item 178875812.

K+V channel CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:1 Tested

AID:: 1788758

Summary Related BioAssays by Target

Select item 178839013.

K+ channel (volt-dependent) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:1 Tested

AID:: 1788390

Summary Related BioAssays by Target

Select item 178831414.

K+ channel (Volt-dependent) Ligand binding assay

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:1 Tested

AID:: 1788314

Summary Related BioAssays by Target

Select item 178718915.

K+ channel (Volt-dependent) CEREP screen

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:1 Tested

AID:: 1787189

Summary Related BioAssays by Target

Select item 178047216.

Inhibition of recombinant human KCNQ1 expressed in CHO-K1 cells at 100 uM by automated Qpatch clamp assay relative to control

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1780472

Summary PubMed Citation Related BioAssays by Target

Select item 175448017.

Inhibition of KvLQT1/mink (unknown origin) by voltage clamp method

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily E member 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1754480

Summary PubMed Citation Related BioAssays by Target

Select item 173849918.

Inhibition of recombinant human KCNQ1 expressed in CHO-K1 cells at 100 uM by automated Qpatch clamp assay relative to control

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1738499

Summary PubMed Citation Related BioAssays by Target

Select item 173849819.

Inhibition of recombinant human KCNQ1 expressed in CHO-K1 cells at 30 uM by automated Qpatch clamp assay relative to control

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1738498

Summary PubMed Citation Related BioAssays by Target

Select item 173849720.

Inhibition of recombinant human KCNQ1 expressed in CHO-K1 cells at 3 uM by automated Qpatch clamp assay relative to control

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily KQT member 1

Assay data:1 Tested

AID:: 1738497

Summary PubMed Citation Related BioAssays by Target

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Proteins (25)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (38)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (9)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Summary (3)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (74)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
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Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (174)
BioAssays reporting BioActivity of chemical reagents
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BioAssays reporting BioActivity of RNAi reagents

Assay Project (25)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (141)
BioAssays extracted from the literature
NIH MLP (25)
BioAssays deposited by the NIH Molecular Libraries Program
Other (21)
BioAssays deposited by other experimentalists

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