BioAssay by Target (List) for Gene (Select 4317) - PubChem BioAssay - NCBI

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Select item 3109111.

Inhibition of MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:43 Active, 39 Activity ≤ 1 µM, 48 Tested

AID:: 310911

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3708772.

Inhibition of human recombinant MMP8 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:2 Active, 4 Tested

AID:: 370877

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 3706323.

Inhibition recombinant MMP8 expressed in CHO-K1 cells at 100 uM

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:12 Tested

AID:: 370632

Summary PubMed Citation Related BioAssays by Target

Select item 3628784.

Inhibition of human recombinant MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 7 Tested

AID:: 362878

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3598465.

Inhibition of MMP8 catalytic domain

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 359846

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3494016.

Inhibition of MMP8 up to 100 uM

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:3 Tested

AID:: 349401

Summary PubMed Citation Related BioAssays by Target

Select item 3493767.

Inhibition of MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:12 Active, 9 Activity ≤ 1 µM, 20 Tested

AID:: 349376

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3470098.

Binding affinity to MMP8 assessed as enzyme mediated cleavage of compound by measuring increase in fluorescence after 16 hrs by HPLC-MS

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:1 Tested

AID:: 347009

Summary PubMed Citation Related BioAssays by Target

Select item 3465919.

Inhibition of human recombinant MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 346591

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 31777110.

Inhibition of human recombinant MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:2 Tested

AID:: 317771

Summary PubMed Citation Related BioAssays by Target

Select item 31752311.

Inhibition of MMP8 catalytic domain

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:1 Tested

AID:: 317523

Summary PubMed Citation Related BioAssays by Target

Select item 31655212.

Inhibition of human MMP8 at 10 uM

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:2 Tested

AID:: 316552

Summary PubMed Citation Related BioAssays by Target

Select item 31583813.

Inhibition of MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:1 Tested

AID:: 315838

Summary PubMed Citation Related BioAssays by Target

Select item 31521414.

Binding affinity to MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:1 Active, 1 Tested

AID:: 315214

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 31434115.

Inhibition of MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:2 Active, 4 Tested

AID:: 314341

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 31370316.

Inhibition of MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:1 Active, 1 Tested

AID:: 313703

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37088817.

Inhibition of human recombinant MMP8 by fluorogenic substrate assay

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:2 Active, 1 Activity ≤ 1 µM, 4 Tested

AID:: 370888

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 30334018.

Inhibition of MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:17 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 22 Tested

AID:: 303340

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 29988319.

Inhibition of MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 299883

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 29906020.

Inhibition of MMP8

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:1 Tested

AID:: 299060

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (3)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (168)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (46)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (141)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (185)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (10)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (243)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (3)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (232)
BioAssays extracted from the literature
NIH MLP (3)
BioAssays deposited by the NIH Molecular Libraries Program
Other (21)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 4317) (256)
PubChem BioAssay
SUB2 ATP-dependent RNA helicase SUB2 [Saccharomyces cerevisiae S288C]
SUB2 ATP-dependent RNA helicase SUB2 [Saccharomyces cerevisiae S288C]
Gene ID:851475

Gene
Gene Links for GEO Profiles (Select 6190206) (1)
Gene
Pre-mRNA splicing factor mutants at restrictive temperature: time course
Pre-mRNA splicing factor mutants at restrictive temperature: time course
Accession: GDS759

GEO DataSets
Related DataSets for GEO Profiles (Select 6190204) (1)
GEO DataSets

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