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Agonist activity at recombinant human c-Mpl receptor transfected in BA/F3 cells assessed as increase in cell proliferation by cell counting analysis
Assay data:4 Active, 3 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Human Thrombopoietin receptor (Prolactin receptor family)
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at human TPO receptor expressed in mouse BaF-B03 cells assessed as induction of cell proliferation after 20 hrs by WST-1 assay
Assay data:5 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Binding affinity to c-Mpl (unknown origin) expressed in rat NIH-3T3 cells after 48 hrs by dual-glo luciferase reporter gene assay relative to control
Assay data:3 Active, 4 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Inhibition of human TPOR expressed in human BaF3 cells at 300 nM
Assay data:7 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human TPOR expressed in human BaF3 cells at 150 nM
Inhibition of human TPOR expressed in human BaF3 cells
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Agonist activity at human recombinant TPO receptor expressed in mouse BaF3 cells after 24 hrs
Assay data:3 Active, 5 Activity ≤ 1 µM, 5 Tested
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