BioAssay by Target (List) for Gene (Select 479) - PubChem BioAssay - NCBI

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Select item 1468681.

Inhibition activity against Na+/K+ ATPase (relative potency in comparison to digitoxigenin)

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:1 Tested

AID:: 146868

Summary PubMed Citation Related BioAssays by Target

Select item 19042.

siRNA Circadian Assay

Source:: The Genomics Institute of the Novartis Research Foundation (GNF)

Assay data:527 Active, 33364 Tested

AID:: 1904

Summary PubMed Citation Related BioAssays by Depositor

Select item 789083.

Evaluated for the inhibition of H+/K+ ATPase enzyme from fundic mucosa of white rabbits

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:23 Tested

AID:: 78908

Summary PubMed Citation Related BioAssays by Target

Select item 789094.

Evaluated for the inhibition of H+/K+ ATPase enzyme from fundic mucosa of white rabbits at 100 uM

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:1 Active, 31 Tested

AID:: 78909

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 789145.

Evaluated for the inhibition of H+/K+ ATPase enzyme from fundic mucosa of white rabbits at 100 uM

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:1 Tested

AID:: 78914

Summary PubMed Citation Related BioAssays by Target

Select item 790876.

Activity was evaluated by measuring the inhibition of isolated rat H+/K+ ATPase at 10 mg/kg; Inactive

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:1 Tested

AID:: 79087

Summary PubMed Citation Related BioAssays by Target

Select item 1468577.

Compound was evaluated for its ability to inhibit the specific [3H]-ouabain binding to dog kidney Na+/K+ ATPase

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:10 Active, 9 Activity ≤ 1 µM, 10 Tested

AID:: 146857

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 1468598.

Inhibitory activity against Na+/K+ ATPase

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 146859

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 1468609.

Inhibitory activity against Na+/K+ ATPase measured by 32P-ATP hydrolysis method

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:1 Tested

AID:: 146860

Summary PubMed Citation Related BioAssays by Target

Select item 14686210.

Inhibitory activity against Na+/K+ ATPase was determined in guinea pig

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:1 Tested

AID:: 146862

Summary PubMed Citation Related BioAssays by Target

Select item 14686411.

Tested against canine renal Na+/K+ ATPase

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:1 Tested

AID:: 146864

Summary PubMed Citation Related BioAssays by Target

Select item 14686512.

Compound at 100 uM was tested in vitro for the inhibition of dog kidney Na+/K+ ATPase

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:5 Tested

AID:: 146865

Summary PubMed Citation Related BioAssays by Target

Select item 14686613.

Inhibition activity against Na+/K+ ATPase at 100 MicroM Concentration

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:1 Tested

AID:: 146866

Summary PubMed Citation Related BioAssays by Target

Select item 14686714.

Inhibitory activity against Na+/K+ ATPase at 10 uM Concentration

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:1 Tested

AID:: 146867

Summary PubMed Citation Related BioAssays by Target

Select item 150858815.

RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:790 Active, 18119 Tested

AID:: 1508588

Select item 14687116.

Inhibitory activity against rat kidney Na+/K+ ATPase was determined by fiske subbarow method

Source:: ChEMBL

Protein Target:: Potassium-transporting ATPase alpha chain 2

Assay data:3 Tested

AID:: 146871

Summary Related BioAssays by Target

Select item 62409917.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 65181018.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 65181119.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

Select item 74312120.

Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:167 Active, 26449 Tested

AID:: 743121

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (3)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (2)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (8)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (14)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (14)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (12)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 479) (27)
PubChem BioAssay
Peripheral blood-derived monocytes response to lipopolysaccharide: time course
Peripheral blood-derived monocytes response to lipopolysaccharide: time course
Accession: GDS2856

GEO DataSets
Related DataSets for GEO Profiles (Select 42370653) (1)
GEO DataSets
Mus musculus prostaglandin I2 (prostacyclin) synthase (Ptgis), transcript varian...
Mus musculus prostaglandin I2 (prostacyclin) synthase (Ptgis), transcript variant 1, mRNA
gi|2500415802|ref|NM_008968.5|

Nucleotide

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