BioAssay by Target (List) for Gene (Select 5141) - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

Items: 1 to 20 of 533

<< First< Prev

Page of 27

Select item 19624971.

Phosphodiesterase PDE4 Eurofins Panlabs panel

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Tested

AID:: 1962497

Summary Related BioAssays by Target

Select item 19624702.

Panlabs assay PDE4A1A

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Assay data:1 Tested

AID:: 1962470

Summary Related BioAssays by Target

Select item 19618143.

Compound was evaluated for inhibition of human PDE4A in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Assay data:46 Active, 10 Activity ≤ 1 µM, 927 Tested

AID:: 1961814

Summary Related BioAssays by Target

Select item 19341004.

Inhibition of human recombinant PDE4A incubated for 30 mins by Scintillation Proximity Assay

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1934100

Summary Related BioAssays by Target

Select item 19333195.

Inhibition of human recombinant PDE4A

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1933319

Summary Related BioAssays by Target

Select item 19244606.

Inhibition of human PDE4A

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Assay data:1 Tested

AID:: 1924460

Summary Related BioAssays by Target

Select item 19244547.

Binding affinity to human PDE4 assessed as dissociation constant

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1924454

Summary Related BioAssays by Target

Select item 19244498.

Inhibition of human PDE4

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Tested

AID:: 1924449

Summary Related BioAssays by Target

Select item 19235779.

Inhibition of PDE4A (unknown origin) using cAMP as substrate incubated for 30 mins by Ba(OH)2 precipitation assay based scintillation counter

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1923577

Summary Related BioAssays by Target

Select item 192355810.

Inhibition of PDE4 (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:3 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 3 Tested

AID:: 1923558

Summary Related BioAssays by Target

Select item 192072711.

Inhibition of human PDE4

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B; ...
Total:: 4

Assay data:1 Tested

AID:: 1920727

Summary Related BioAssays by Target

Select item 192072212.

Inhibition of human PDE4 assessed as inhibition constant

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4C; ...
Total:: 4

Assay data:1 Tested

AID:: 1920722

Summary Related BioAssays by Target

Select item 191466713.

Selectivity interaction (PDE panel (enzymatic activity assay)) EUB0000751a PDE4A

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Assay data:1 Active, 1 Tested

AID:: 1914667

Summary Compounds, Active Related BioAssays by Target

Select item 191461514.

Selectivity interaction (PDE panel (enzymatic assay)) EUB0000744a PDE4A

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Assay data:1 Active, 1 Tested

AID:: 1914615

Summary Related BioAssays by Target

Select item 190312315.

Inhibition of PDE4A (unknown origin) at 1 to 10 uM by fluorescence polarization based assay

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Assay data:2 Tested

AID:: 1903123

Summary PubMed Citation Related BioAssays by Target

Select item 189584316.

Inhibition of human PDE4 expressed in Sf9 cells by non-linear regression analysis

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1895843

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187151417.

Inhibition of PDE4 (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Active, 1 Tested

AID:: 1871514

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 185926818.

Inhibition of cAMP-specific 3',5'-cyclic phosphodiesterase (unknown origin)

Source:: ChEMBL

Protein Targets:: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; ...
Total:: 23

Assay data:2 Active, 1 Activity ≤ 1 µM, 4 Tested

AID:: 1859268

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185103919.

Inhibition of human PDE4 at 10 uM measured by radioligand binding assay relative to control

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Tested

AID:: 1851039

Summary PubMed Citation Related BioAssays by Target

Select item 181374120.

Inhibition of human PDE4 at 10 uM relative to control

Source:: ChEMBL

Protein Targets:: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; ...
Total:: 23

Assay data:1 Tested

AID:: 1813741

Summary PubMed Citation Related BioAssays by Target

<< First< Prev

Page of 27

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (303)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (77)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (251)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (358)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (520)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (510)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (22)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Recent activity

Clear Turn Off Turn On

BioAssay by Target (List) for Gene (Select 5141) (533)
PubChem BioAssay
dbVar for Gene (Select 5141) (275)
dbVar

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay