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Inhibition of CDK (unknown origin)
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of CDK14 (unknown origin) incubated for 120 mins in presence of ATP by HotSpot kinase assay
Assay data:2 Tested
Inhibition of CDK14 (unknown origin) by Kinomescan method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of CDK14/cyclinY (unknown origin) at 10 uM relative to control
Inhibition of CDK14 (unknown origin) incubated for 6 hrs by NanoBRET assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of GST-tagged human recombinant full-length CDK14 (2 to end residues) expressed in baculovirus expression system preincubated for 30 mins by Lanthascreen Eu-Kinase binding assay
PFTK1 DiscoveRx kinase panel
SummaryRelated BioAssays by Target
CDK14/cyclinY(h) Kinase panel
Inhibition of CDK14/cyclin-Y (unknown origin) at 1 uM
Inhibition of CDK14/Cyclin Y (unknown origin) assessed as residual activity at 1 uM in presence of 33P-ATP incubated for 2 hrs by kinase selectivity assay
KinomeScan assay: inhibition of PFTK1
Assay data:108 Tested
PFTAIRE1(CD14CGS1) Takeda global kinase panel
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Target
CDK14/cyclinY(h) Eurofins Kinase panel
CDK14/cyclinY(h) Millipore kinase panel
CDK14 (PFTK1)/CYC Invitrogen Lab (UK) kinase screen (BI)
Inhibition of human CDK14/cyclin-Y using RB protein as substrate incubated for 2 hrs by [gamma-33P]-ATP assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human PFTK1 assessed as percent of control at 2000 nM by KINOMEscan assay relative to control
Inhibition of DNA-tagged human PFTK1 assessed as percent of control at 50000 nM by qPCR analysis relative to control
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