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Binding affinity to Cyclophilin A
Assay data:2 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to human cyclophilin A assessed as compound-enzyme complex formation at 1:1 protein to compound ratio by NMR analysis
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Inhibition of PPIase activity of human recombinant cyclophilin-A using succinyl-Ala-Ala-Pro-Phe-4-nitroanilide as substrate at 100 uM pretreated for 3 hrs before substrate addition by spectrophotometry
Assay data:1 Tested
Inhibition of PPIase activity of human recombinant cyclophilin-A using succinyl-Ala-Ala-Pro-Phe-4-nitroanilide as substrate at 100 uM by protease coupled assay
Inhibition of PPIase activity of human recombinant cyclophilin-A using succinyl-Ala-Ala-Pro-Phe-4-nitroanilide as substrate by protease coupled assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to human recombinant cyclophilin-A up to 25 uM by isothermal titration calorimetry assay
Binding affinity to human recombinant cyclophilin-A by isothermal titration calorimetry assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Binding affinity to human cyclophilin A by fluorescence polarization assay
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of PPIase activity of Cyclophilin A by Spectrophotometry
Assay data:2 Active, 2 Activity ≤ 1 µM, 4 Tested
Inhibition of human recombinant cyclophilin-associted cis-trans propyl isomerase activity
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 4 Tested
Inhibition of fluorescein labeled cyclosporin binding to Cyp18 by fluorescence polarization competition assay
Inhibition of cyclosporin binding to Cyp18 by fluorescence polarization competition assay
Inhibition of Cyclophilin 18 PPIase activity
Binding affinity to cyclophilin A by ELISA
Assay data:20 Active, 20 Activity ≤ 1 µM, 20 Tested
Inhibition of cyclophilin A
Inhibition of PPIase activity of cyclophilin 18 at 200 nM by protease coupled assay
Assay data:1 Active, 1 Tested
Binding affinity to human cyclophilin 18 assessed as reduction in calcineurin activity
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