BioAssay by Target (List) for Gene (Select 5582) - PubChem BioAssay - NCBI

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Select item 2684871.

Inhibition of PKC

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 11

Assay data:1 Tested

AID:: 268487

Summary PubMed Citation Related BioAssays by Target

Select item 2776402.

Inhibition of PKC

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 11

Assay data:4 Active, 5 Activity ≤ 1 µM, 6 Tested

AID:: 277640

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2771283.

Inhibition of PKC at 25 uM by ELISA

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 11

Assay data:1 Tested

AID:: 277128

Summary PubMed Citation Related BioAssays by Target

Select item 2771114.

Inhibition of PKC in human peripheral leucocytes at 5 uM by ELISA

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 11

Assay data:1 Tested

AID:: 277111

Summary PubMed Citation Related BioAssays by Target

Select item 2766255.

Inhibition of PKC

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 11

Assay data:1 Tested

AID:: 276625

Summary PubMed Citation Related BioAssays by Target

Select item 2742076.

Inhibition of PKC-mediated phosphorylation of neurogranin at 100 uM

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 11

Assay data:19 Tested

AID:: 274207

Summary PubMed Citation Related BioAssays by Target

Select item 2736477.

Percentage activity of human PKC gamma in the presence of 10 uM of compound and 10 uM of ATP in comparison with control

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:1 Tested

AID:: 273647

Summary PubMed Citation Related BioAssays by Target

Select item 2713928.

Inhibition of PKCgamma

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 271392

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2688469.

Inhibition of PKC

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 11

Assay data:1 Active, 1 Tested

AID:: 268846

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 28122410.

Inhibition of PKC gamma

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:3 Tested

AID:: 281224

Summary PubMed Citation Related BioAssays by Target

Select item 26741311.

Inhibition of PKC at 1 uM

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 11

Assay data:1 Tested

AID:: 267413

Summary PubMed Citation Related BioAssays by Target

Select item 26701412.

Residual activity at human PKCgamma at 10 uM in presence of 10 uM ATP relative to control

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:1 Tested

AID:: 267014

Summary PubMed Citation Related BioAssays by Target

Select item 26690713.

Inhibition of PKCgamma

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:1 Tested

AID:: 266907

Summary PubMed Citation Related BioAssays by Target

Select item 26659314.

Inhibition of PKCgamma

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:1 Active, 1 Tested

AID:: 266593

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 26612415.

Inhibition of PKCgamma

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:5 Tested

AID:: 266124

Summary PubMed Citation Related BioAssays by Target

Select item 26559216.

Inhibition of PKC gamma at 5 uM ATP

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:4 Active, 4 Activity ≤ 1 µM, 5 Tested

AID:: 265592

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 26428517.

Induction of GFP-tagged PKC gamma translocation in HeLa cells measured as ratio of fluorescence intensity in plasma membrane to cytosol at 0.5 uM

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:2 Tested

AID:: 264285

Summary PubMed Citation Related BioAssays by Target

Select item 26428418.

Induction of GFP-tagged PKC gamma translocation in HeLa cells measured as ratio of fluorescence intensity in plasma membrane to cytosol at 1 uM

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:2 Tested

AID:: 264284

Summary PubMed Citation Related BioAssays by Target

Select item 31218519.

Displacement of [3H]PDBu from PKCgamma C1A domain

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:3 Active, 2 Activity ≤ 1 µM, 5 Tested

AID:: 312185

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 32101220.

Displacement of [3H]PDBu from PKCgamma C1B domain

Source:: ChEMBL

Protein Target:: Protein kinase C gamma type

Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested

AID:: 321012

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets
RNAi Target, Active (9)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (183)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (15)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (114)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (214)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (42)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (513)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (46)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (492)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (64)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 5582) (559)
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gi|1674988382|ref|NM_001316329.2|

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