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Agonist activity at human NMUR2 expressed in HEK293 cells at 1 nM by calcium mobilization assay relative to NMU
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Human NMU2 receptor (Neuromedin U receptors)
Assay data:15 Active, 15 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at recombinant human NMU2 expressed in HEK293 cells assessed as change in intracellular calcium flux at 10 uM by fluorescence assay relative to human NmU
Assay data:17 Tested
Agonist activity at recombinant human NMU2 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assay relative to human NmU
Assay data:14 Tested
Agonist activity at recombinant human NMU2 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assay
Assay data:23 Active, 3 Activity ≤ 1 nM, 17 Activity ≤ 1 µM, 23 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Intrinsic agonist activity at human NMUR2 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging method
Agonist activity at human NMUR2 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging method
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Agonist activity at human NMUR2 expressed in CHO cells assessed as intracellular calcium flux at 1 and 10 nM by Fluo-4 AM dye based fluorometric imaging method relative to 1000 nM human neuromedin U
Assay data:8 Active, 13 Tested
Agonist activity at human NMUR2 expressed in CHO cells at 10'-12 to 10'-6 M by calcium mobilization assay relative to NMU
Assay data:2 Tested
Agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Partial agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Agonist activity at human NMUR2 expressed in CHO cells assessed as concentration required to induce 50% response by calcium mobilization assay relative to NMU
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Agonist activity at human NMUR2 expressed in HEK293 cells at 10 nM by calcium mobilization assay relative to NMU
Agonist activity at human NMUR2 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based topcount assay
Assay data:41 Active, 3 Activity ≤ 1 nM, 31 Activity ≤ 1 µM, 41 Tested
Agonist activity at human NMUR2 expressed in HEK293 cells at 1 to 100 nM by calcium mobilization assay relative to NMU
Assay data:19 Active, 28 Tested
Agonist activity at human NMU2R transfected in HEK293 cells after 7 hrs by luciferase reporter gene assay
Assay data:3 Active, 33 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
SummaryPubMed Citation
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