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Inhibition of CIP2A in human A549 cells assessed as downregulation of p-AKT protein expression at 1 to 10 uM after 24 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Inhibition of CIP2A in human SKHEP1 cells at 5 uM after 30 hrs by Western blot analysis
Assay data:2 Active, 3 Tested
Inhibition of CIP2A-mediated PP2A-dependent AKT phosphorylation in human SKHEP1 cells at 5 uM after 30 hrs by Western blot analysis
Inhibition of CIP2A-mediated PP2A-dependent AKT phosphorylation in human SKHEP1 cells at 5 uM after 30 hrs by Western blot analysis in presence of okadaic acid
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Inhibition of CIP2A in human A549 cells assessed as potentiation of cisplatin-induced PARP cleavage at 3.5 uM after 24 hrs by Western blot analysis
Inhibition of CIP2A in human NCI-H1975 cells assessed as potentiation of cisplatin-induced PARP cleavage at 1 uM after 24 hrs by Western blot analysis
Inhibition of CIP2A in human A549 cells assessed as potentiation of cisplatin-induced cell growth inhibition at 3.5 uM after 24 hrs by MTT assay
Inhibition of CIP2A in human NCI-H1975 cells assessed as potentiation of cisplatin-induced cell growth inhibition at 1 uM after 24 hrs by MTT assay
Inhibition of CIP2A in human A549 cells assessed as induction of PP2A activity at 5 uM after 4 to 8 hrs by Western blot analysis
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Inhibition of CIP2A in human A549 cells assessed as downregulation of c-Myc protein expression at 1 to 10 uM after 24 hrs by Western blot analysis
Inhibition of CIP2A in human NCI-H1975 cells assessed as downregulation of p-AKT protein expression at 1 to 2.5 uM after 24 hrs by Western blot analysis
Inhibition of CIP2A in human NCI-H1975 cells assessed as downregulation of c-Myc protein expression at 1 to 2.5 uM after 24 hrs by Western blot analysis
Induction of CIP2A proteolysis in human A549 cells at 5 uM after 4 hrs in presence of protein synthesis inhibitor cycloheximide
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