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Inhibition of SENP2 (unknown origin)
Assay data:12 Active, 14 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of recombinant human SENP2 in presence of DTT by FRET assay
Assay data:2 Active, 2 Tested
Inhibition of His-tagged human SENP2 (364 to 589 residues) expressed in Escherichia coli (DE3) using YFP-SUMO-ECFP as substrate incubated for 15 mins by Coomassie staining based SDS-PAGE analysis
Assay data:1 Active, 1 Tested
Inhibition of human SENP2 using QTGG-AFC as substrate by fluorescence based analysis
Inhibition of human SENP2 using AMC-tagged SUMO1 as substrate incubated for 10 mins by fluorescence based analysis
Enzyme Kinetic Assay from US Patent US11041859: "Methods of identifying SENP1 inhibitors"
Assay data:10 Active, 10 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
SUMO Cleavage Assay from Article 10.1021/cb400177q: "Identification and Characterization of a New Chemotype of Noncovalent SENP Inhibitors."
Assay data:7 Active, 10 Tested
Fluorogenic Assay from Article 10.1016/j.chembiol.2011.05.008: "Development of small molecule inhibitors and probes of human SUMO deconjugating proteases."
Assay data:5 Active, 2 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding Assay from US Patent US9791447: "Methods of identifying SENP1 inhibitors"
Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 10 mins followed by substrate addition and measured after 25 min by Coomassie blue staining based SDS-PAGE analysis
Assay data:33 Active, 2 Activity ≤ 1 µM, 53 Tested
Inhibition of SNEP2 (unknown origin) using CyPet-pre-SUMO-1-YPet as substrate incubated for 1 hr by FRET assay
Inhibition of human His-tagged SENP2 (364 to 589 residues) expressed in Escherichia coli (DE3) cells using DUB-Glo as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by luciferase assay
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of human recombinant His-tagged SENP2 (363 to 589 residues) expressed in Escherichia coli BL21 (DE3) using RanGAP-SUMO as substrate incubated for 10 mins prior to substrate addition followed by further 25 mins incubation by krypton dye based fluorescence imaging method
Inhibition of human recombinant His-tagged SENP2 (363 to 589 residues) expressed in Escherichia coli BL21 (DE3) using RanGAP-SUMO as substrate incubated for 10 mins prior to substrate addition followed by further 25 mins incubation by coomassie blue staining based SDS-PAGE/Odyssey infrared scanning assay
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
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