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Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as increase cell impedance at 250 to 750 nM measured every 10 to 30 secs for 1 hr by real time cell analyzer method
Assay data:2 Active, 2 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay relative to forskolin
Assay data:167 Tested
SummaryRelated BioAssays by Target
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
Assay data:95 Active, 18 Activity ≤ 1 µM, 167 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Agonist activity at human RXFP1 receptor expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
Assay data:1 Active, 1 Tested
qHTS Assay for Antagonists of the Relaxin Receptor RXFP1
Assay data:2064 Active, 352386 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested
Displacement of europium-labelled H2 relaxin from RXFP1 expressed in HEK-293T cells
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of RXFP1 expressed in HEK-293T cells assessed as induction of cAMP accumulation after 6 hrs by beta galactosidase reporter gene assay
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
qHTS Assay for Agonists of the Relaxin Receptor RXFP1: Cell Impedance
Assay data:5 Active, 5 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
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