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Binding affinity to 80S ribosome in human HuH7 cells harboring human PCSK9 (1 to 152 residues)-proLuc assessed as inhibition of PCSK9 mRNA translation at 20 uM after overnight incubation by luciferase reporter gene assay relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to RPL17 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to 60S ribosomal protein L35 in human Hela cells lysates assessed as protein enrichment by measuring normalized heavy/light ratio at by nano-LC-ESIMS/MS analysis
Inhibition of ribosome-mediated translation of PCDH15 R245X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay
Assay data:5 Active, 5 Tested
Inhibition of ribosome-mediated translation of CFTR W1282X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay
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