BioAssay by Target (List) for Gene (Select 6332) - PubChem BioAssay - NCBI

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Select item 12071481.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Tested

AID:: 1207148

Summary PubMed Citation Related BioAssays by Target

Select item 12248302.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout

Source:: Iain Fraser

Assay data:2853 Active, 18113 Tested

AID:: 1224830

Summary Related BioAssays by Same Project

Select item 12071733.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Tested

AID:: 1207173

Summary PubMed Citation Related BioAssays by Target

Select item 12071724.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Tested

AID:: 1207172

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 12071655.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1207165

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 12071636.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Tested

AID:: 1207163

Summary PubMed Citation Related BioAssays by Target

Select item 12071627.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Tested

AID:: 1207162

Summary PubMed Citation Related BioAssays by Target

Select item 12071618.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1207161

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 12071609.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Tested

AID:: 1207160

Summary PubMed Citation Related BioAssays by Target

Select item 120715910.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Tested

AID:: 1207159

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 120715811.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Tested

AID:: 1207158

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 120715612.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Tested

AID:: 1207156

Summary PubMed Citation Related BioAssays by Target

Select item 120715413.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Tested

AID:: 1207154

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 120715114.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Tested

AID:: 1207151

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 120715015.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Tested

AID:: 1207150

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 124410616.

Inhibition of Nav2.1 channel (unknown origin)

Source:: ChEMBL

Protein Target:: Sodium channel protein type 7 subunit alpha

Assay data:1 Tested

AID:: 1244106

Summary PubMed Citation Related BioAssays by Target

Select item 120714717.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Tested

AID:: 1207147

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 120714618.

Inhibition of Na channel (species unknown)

Source:: ChEMBL

Protein Targets:: Sodium channel protein type 1 subunit alpha; ...
Total:: 10

Assay data:1 Active, 1 Tested

AID:: 1207146

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 115958419.

A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:2442 Active, 18052 Tested

AID:: 1159584

Summary PubMed Citation

Select item 115957820.

A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:1034 Active, 18120 Tested

AID:: 1159578

Summary Related BioAssays by Depositor

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (19)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (3)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (9)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (26)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (45)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (34)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (23)
BioAssays deposited by other experimentalists

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