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Inhibition of NET (unknown origin)
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of [3H]-nisoxetine from recombinant human NET stably expressed in HEK cells measured after 90 mins by microbeta scintillation counting method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of NAT (unknown origin)
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation counting
Assay data:13 Active, 10 Activity ≤ 1 µM, 13 Tested
Inhibition of NET (unknown origin) at 10 uM relative to control
Assay data:9 Tested
Inhibition of human norepinephrine transporter at 1 uM relative to control
Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cells
Assay data:13 Active, 11 Activity ≤ 1 µM, 13 Tested
Inhibition of [3H]NE uptake at human NET K463N mutant expressed in african green monkey COS1 cells after 48 hrs
Inhibition of [3H]NE uptake at human NET K189H mutant expressed in african green monkey COS1 cells after 48 hrs
Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells at 1 uM
Assay data:3 Tested
Inhibition of NET at 10 uM
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