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STK6 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of Aurora A (unknown origin) at 10 uM by biochemical hotspot kinase assay
Inhibition of Aurora A (unknown origin)
Inhibition of AuroraA (unknown origin)
Inhibition of recombinant full length His-tagged human Aurora A expressed in baculovirus expression system by FRET assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human Aurora A
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue at 8XMEC measured after 6 hrs by immunofluorescence staining analysis
Assay data:4 Tested
Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue at 100 nM measured after 6 hrs by immunofluorescence staining analysis
Assay data:1 Active, 1 Tested
Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue by measuring residual enzyme activity at 40 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100+/-1%)
Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue by measuring residual enzyme activity at 20 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-1%)
Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue by measuring residual enzyme activity at 10 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-1%)
Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue by measuring residual enzyme activity at 0.312 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-1%)
Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue by measuring residual enzyme activity at 0.156 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-1%)
Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue by measuring residual enzyme activity at 0.078 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-1%)
Inhibition of AURA (unknown origin)
Inhibition of human partial length Aurora-A (E122/K401) expressed in mammalian system at 1 uM by KINOMEscan analysis relative to control
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