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Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Inhibition of Prcp in mouse Neuro2a cells at 3 nM after 4 hrs by ABPP-SILAC assay
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate after 30 mins by continuous fluorometric assay
Assay data:12 Active, 1 Activity ≤ 1 nM, 12 Activity ≤ 1 µM, 12 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assay
Assay data:19 Active, 2 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 19 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of mouse PrCP
Assay data:22 Active, 6 Activity ≤ 1 nM, 22 Activity ≤ 1 µM, 22 Tested
Assay data:31 Active, 5 Activity ≤ 1 nM, 31 Activity ≤ 1 µM, 31 Tested
Late stage assay provider results from the probe development effort to identify selective inhibitors of LYPLA2: LCMS-based Activity-Based Protein Profiling (ABPP) SILAC selectivity analysis in vitro
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage assay provider results from the probe development effort to identify selective inhibitors of LYPLA1: LCMS-based Activity-Based Protein Profiling (ABPP) SILAC selectivity analysis in vitro
Inhibition of PrCP-mediated angiotensin3 cleavage in mouse plasma using Mca-Ala-Lys-Dnp as substrate for 8 mins by LC/MS analysis
Assay data:10 Active, 7 Activity ≤ 1 µM, 11 Tested
Inhibition of mouse recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assay
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of mouse recombinant PrCP assessed as angiotensin 3 cleavage after 8 mins by LC/MS analysis
Assay data:6 Active, 4 Activity ≤ 1 µM, 13 Tested
Inhibition of mouse recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate after 30 mins by fluorescence analysis
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Inhibition of mouse PrCP in 30 mg/kg, po qd for 5 days established diet-induced obese wild type C57BL/6 mouse heat inactivated brain homogenates measured on day 6
Assay data:1 Tested
Inhibition of mouse PrCP in 30 mg/kg, po qd for 5 days established diet-induced obese wild type C57BL/6 mouse heat inactivated plasma measured on day 6
Inhibition of mouse PrCP in 30 mg/kg, po administered qd for 2 days established diet-induced obese C57BL/6 mouse heat inactivated plasma
Inhibition of mouse PrCP in 10 mg/kg, po administered qd for 2 days established diet-induced obese C57BL/6 mouse heat inactivated plasma
Inhibition of mouse PrCP in 3 mg/kg, po administered qd for 2 days established diet-induced obese C57BL/6 mouse heat inactivated plasma
Inhibition of PrCP in mouse plasma assessed as angiotensin 3 cleavage by whole serum shift assay
Assay data:10 Active, 12 Activity ≤ 1 µM, 12 Tested
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